IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives

Por Mondesir, Johanna, Willekens, Christophe, Touat, Mehdi, de Botton, Stéphane
Publicado no J Blood Med (2016)

Myeloid Sarcoma of the Nasopharynx Mimicking an Aggressive Lymphoma

Por Raphael, Jacques, Valent, Alexander, Hanna, Colette, Auger, Nathalie, Casiraghi, Odile, Ribrag, Vincent, De Botton, Stephane, Saada, Veronique
Publicado em 2013

Erlotinib antagonizes ABC transporters in acute myeloid leukemia

Por Lainey, Elodie, Sébert, Marie, Thépot, Sylvain, Scoazec, Marie, Bouteloup, Cyrielle, Leroy, Carole, De Botton, Stéphane, Galluzzi, Lorenzo, Fenaux, Pierre, Kroemer, Guido
Publicado em 2012

Chromosomal Minimal Critical Regions in Therapy-Related Leukemia Appear Different from Those of De Novo Leukemia by High-Resolution aCGH

Por Itzhar, Nathalie, Dessen, Philippe, Toujani, Saloua, Auger, Nathalie, Preudhomme, Claude, Richon, Catherine, Lazar, Vladimir, Saada, Véronique, Bennaceur, Anelyse, Bourhis, Jean Henri, de Botton, Stéphane, Bernheim, Alain
Publicado em 2011

Successful Outcome of Disseminated Fusarium Infection with Skin Localization Treated with Voriconazole and Amphotericin B-Lipid Complex in a Patient with Acute Leukemia

Por Durand-Joly, Isabelle, Alfandari, Serge, Benchikh, Zinnédine, Rodrigue, Marion, Espinel-Ingroff, Ana, Catteau, Benoit, Cordevant, Christophe, Camus, Daniel, Dei-Cas, Eduardo, Bauters, Francis, Delhaes, Laurence, De Botton, Stéphane
Publicado em 2003

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

Por Plo, Isabelle, Zhang, Yanyan, Le Couédic, Jean-Pierre, Nakatake, Mayuka, Boulet, Jean-Michel, Itaya, Miki, Smith, Steven O., Debili, Najet, Constantinescu, Stefan N., Vainchenker, William, Louache, Fawzia, de Botton, Stéphane
Publicado em 2009

Targeting primary acute myeloid leukemia with a new CXCR4 antagonist IgG1 antibody (PF-06747143)

Por Zhang, Yanyan, Saavedra, Erika, Tang, Ruoping, Gu, Yin, Lappin, Patrick, Trajkovic, Dusko, Liu, Shu-Hui, Smeal, Tod, Fantin, Valeria, De Botton, Stephane, Legrand, Ollivier, Delhommeau, Francois, Pernasetti, Flavia, Louache, Fawzia
Publicado no Sci Rep (2017)

Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia

Por Peterlin, Pierre, Renneville, Aline, Ben Abdelali, Raouf, Nibourel, Olivier, Thomas, Xavier, Pautas, Cécile, de Botton, Stéphane, Raffoux, Emmanuel, Cayuela, Jean-Michel, Boissel, Nicolas, Terré, Christine, Celli-Lebras, Karine, Castaigne, Sylvie, Preudhomme, Claude, Gardin, Claude, Dombret, Hervé
Publicado no Haematologica (2015)

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

Por Kosmider, Olivier, Gelsi-Boyer, Véronique, Ciudad, Marion, Racoeur, Cindy, Jooste, Valérie, Vey, Norbert, Quesnel, Bruno, Fenaux, Pierre, Bastie, Jean-Noël, Beyne-Rauzy, Odile, Stamatoulas, Aspasia, Dreyfus, François, Ifrah, Norbert, de Botton, Stéphane, Vainchenker, William, Bernard, Oliver A., Birnbaum, Daniel, Fontenay, Michaëla, Solary, Eric
Publicado em 2009

Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

Por Amatangelo, Michael D., Quek, Lynn, Shih, Alan, Stein, Eytan M., Roshal, Mikhail, David, Muriel D., Marteyn, Benoit, Farnoud, Noushin Rahnamay, de Botton, Stephane, Bernard, Olivier A., Wu, Bin, Yen, Katharine E., Tallman, Martin S., Papaemmanuil, Elli, Penard-Lacronique, Virginie, Thakurta, Anjan, Vyas, Paresh, Levine, Ross L.
Publicado no Blood (2017)

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

Por Thiollier, Clarisse, Lopez, Cécile K., Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M’Boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D., Ballerini, Paola, Bernard, Olivier A., Pflumio, Françoise, Mercher, Thomas
Publicado em 2012

Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia

Por Stein, Eytan M., DiNardo, Courtney D., Pollyea, Daniel A., Fathi, Amir T., Roboz, Gail J., Altman, Jessica K., Stone, Richard M., DeAngelo, Daniel J., Levine, Ross L., Flinn, Ian W., Kantarjian, Hagop M., Collins, Robert, Patel, Manish R., Frankel, Arthur E., Stein, Anthony, Sekeres, Mikkael A., Swords, Ronan T., Medeiros, Bruno C., Willekens, Christophe, Vyas, Paresh, Tosolini, Alessandra, Xu, Qiang, Knight, Robert D., Yen, Katharine E., Agresta, Sam, de Botton, Stephane, Tallman, Martin S.
Publicado no Blood (2017)

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

Por Merlevede, Jane, Droin, Nathalie, Qin, Tingting, Meldi, Kristen, Yoshida, Kenichi, Morabito, Margot, Chautard, Emilie, Auboeuf, Didier, Fenaux, Pierre, Braun, Thorsten, Itzykson, Raphael, de Botton, Stéphane, Quesnel, Bruno, Commes, Thérèse, Jourdan, Eric, Vainchenker, William, Bernard, Olivier, Pata-Merci, Noemie, Solier, Stéphanie, Gayevskiy, Velimir, Dinger, Marcel E., Cowley, Mark J., Selimoglu-Buet, Dorothée, Meyer, Vincent, Artiguenave, François, Deleuze, Jean-François, Preudhomme, Claude, Stratton, Michael R., Alexandrov, Ludmil B., Padron, Eric, Ogawa, Seishi, Koscielny, Serge, Figueroa, Maria, Solary, Eric
Publicado no Nat Commun (2016)