Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

ανά Shalini Santhakumaran, Anthony Gordon, A. Toby Prevost, Cecilia O’Kane, Daniel F. McAuley, Manu Shankar-Hari
Έκδοση 2019-05-01

Plasma neurofilament light chain protein as a predictor of days in delirium and deep sedation, mortality and length of stay in critically ill patients

ανά Valerie J Page, Leiv Otto Watne, Amanda Heslegrave, Allan Clark, Daniel F McAuley, Robert D Sanders, Henrik Zetterberg
Έκδοση 2022-06-01

Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD.

ανά Suffwan Eltom, Nicole Dale, Kristof R G Raemdonck, Christopher S Stevenson, Robert J Snelgrove, Pradeep K Sacitharan, Chiara Recchi, Silene Wavre-Shapton, Daniel F McAuley, Cecilia O'Kane, Maria G Belvisi, Mark A Birrell
Έκδοση 2014-01-01

Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

ανά Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson
Έκδοση 2018-01-01

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

ανά Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby
Έκδοση 2018-11-01

Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs

ανά Manu Shankar-Hari, Shalini Santhakumaran, A Toby Prevost, Josie K Ward, Timothy Marshall, Claire Bradley, Carolyn S Calfee, Kevin L Delucchi, Pratik Sinha, Michael A Matthay, Jonathan Hackett, Cliona McDowell, John G Laffey, Anthony Gordon, Cecilia M O’Kane, Daniel F McAuley
Έκδοση 2021-07-01

RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxyge...

ανά Gavin D. Perkins, Keith Couper, Bronwen Connolly, J. Kenneth Baillie, Judy M. Bradley, Paul Dark, Anthony De Soyza, Ellen Gorman, Alasdair Gray, Louisa Hamilton, Nicholas Hart, Chen Ji, Ranjit Lall, Nicola McGowan, Scott Regan, Anita K. Simonds, Emma Skilton, Nigel Stallard, Emily Stimpson, Joyce Yeung, Daniel F. McAuley
Έκδοση 2020-07-01

Repair of acute respiratory distress syndrome by stromal cell administration (REALIST): a structured study protocol for an open-label dose-escalation phase 1 trial followed by a ra...

ανά Ellen Gorman, Manu Shankar-Hari, Phil Hopkins, William S. Tunnicliffe, Gavin D. Perkins, Jonathan Silversides, Peter McGuigan, Colette Jackson, Roisin Boyle, Jamie McFerran, Cliona McDowell, Christina Campbell, Margaret McFarland, Jon Smythe, Jacqui Thompson, Barry Williams, Gerard Curley, John G. Laffey, Mike Clarke, Daniel F. McAuley, Cecilia O’Kane
Έκδοση 2022-05-01