Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

Abstract Background Randomised controlled trials (RCTs) enrolling patients with sepsis or acute respiratory distress syndrome (ARDS) generate heterogeneous trial populations. Non-random variation in the treatment effect of an intervention due to differences in the baseline risk of death between pati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shalini Santhakumaran, Anthony Gordon, A. Toby Prevost, Cecilia O’Kane, Daniel F. McAuley, Manu Shankar-Hari
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2019-05-01
Saila:Critical Care
Gaiak:
Sepsis, acute respiratory distress syndrome
Models, statistical
Randomisation
Risk
Study design
Sarrera elektronikoa:http://link.springer.com/article/10.1186/s13054-019-2446-1
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