Bilaketaren emaitzak - Mervyn Singer

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads nork Jean‐Marc Cavaillon, Mervyn Singer, Tomasz Skirecki

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Antibiotic-Induced Immunosuppression—A Focus on Cellular Immunity nork Timothy Arthur Chandos Snow, Mervyn Singer, Nishkantha Arulkumaran

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Creating complex protocells and prototissues using simple DNA building blocks nork Nishkantha Arulkumaran, Mervyn Singer, Stefan Howorka, Jonathan R. Burns

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Real-world inter-observer variability of the sequential organ failure assessment (SOFA) score in intensive care medicine: the time has come for an update: authors’ reply nork Rui Moreno, Andrew Rhodes, Mervyn Singer, Jean-Louis Vincent, On behalf of the authors.

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Microcirculation vs. Mitochondria—What to Target? nork Tamara Merz, Nicole Denoix, Markus Huber-Lang, Mervyn Singer, Peter Radermacher, Oscar McCook

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Mechanisms, therapeutic uses, and developmental perspectives of redox-active thiomolybdates nork Yihan Wu, Khalid S. Alotaibi, Kevin Yu, Tom Durham, Felipe Dal-Pizzol, Mervyn Singer, Alex Dyson

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Butyrate Supplementation Exacerbates Myocardial and Immune Cell Mitochondrial Dysfunction in a Rat Model of Faecal Peritonitis nork Vera B. M. Peters, Nishkantha Arulkumaran, Miranda J. Melis, Charlotte Gaupp, Thierry Roger, Manu Shankar-Hari, Mervyn Singer

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Impact of ghrelin on body composition and muscle function in a long-term rodent model of critical illness. nork Neil E Hill, Kevin G Murphy, Saima Saeed, Rahul Phadke, Darren Chambers, Duncan R Wilson, Stephen J Brett, Mervyn Singer

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Hyperoxia toxicity in septic shock patients according to the Sepsis-3 criteria: a post hoc analysis of the HYPER2S trial nork Julien Demiselle, Martin Wepler, Clair Hartmann, Peter Radermacher, Frédérique Schortgen, Ferhat Meziani, Mervyn Singer, Valérie Seegers, Pierre Asfar, the HYPER2S investigators

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Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset nork Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou

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A randomised controlled trial of plasma exchange compared to standard of care in the treatment of severe COVID-19 infection (COVIPLEX) nork Nishkantha Arulkumaran, Mari Thomas, Matthew Stubbs, Nithya Prasanna, Maryam Subhan, Deepak Singh, Gareth Ambler, Alessia Waller, Mervyn Singer, David Brealey, Marie Scully

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Evaluation of plasma calprotectin as a marker for infection in various clinical settings: a prospective observational study nork Tobias Zimmermann, Timothy Arthur Chandos Snow, Pedro Lopez-Ayala, Ahmed Al-Hindawi, Samer Elkhodair, Nishkantha Arulkumaran, Martin Siegemund, Mervyn Singer, David Brealey

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Risk assessment with gene expression markers in sepsis development nork Albert Garcia Lopez, Sascha Schäuble, Tongta Sae-Ong, Bastian Seelbinder, Michael Bauer, Evangelos J. Giamarellos-Bourboulis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou

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Assessing perioperative risks in a mixed elderly surgical population using machine learning: A multi-objective symbolic regression approach to cardiorespiratory fitness derived fro... nork Pietro Arina, Davide Ferrari, Maciej R Kaczorek, Nicholas Tetlow, Amy Dewar, Robert Stephens, Daniel Martin, Ramani Moonesinghe, Mervyn Singer, John Whittle, Evangelos B Mazomenos

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Executable network of SARS-CoV-2-host interaction predicts drug combination treatments nork Rowan Howell, Matthew A. Clarke, Ann-Kathrin Reuschl, Tianyi Chen, Sean Abbott-Imboden, Mervyn Singer, David M. Lowe, Clare L. Bennett, Benjamin Chain, Clare Jolly, Jasmin Fisher

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Tracheostomy in critically ill patients with SARS 2 COVID-19 infection: a prospective observational multi-center study of short- and long-term outcomes nork Alberto Corona, Vincenzo De Santis, Domenico Vitale, Cecilia Nencini, Antonella Potalivo, Anna Prete, Nicoletta Barzaghi, Sara Tardivo, Marina Terzitta, Anna Malfatto, Luigi Tritapepe, Alessandro Locatelli, Mervyn Singer

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The amphiregulin- epidermal growth factor receptor axis as a therapeutic target in sepsis nork Rebecca Walsh, Timothy Arthur Chandos Snow, Alexandra Z. Martinez, David Brealey, David Brealey, Mervyn Singer, Abhishek Das, Abhishek Das, Nishkantha Arulkumaran, University College London Hospitals Critical Care Research Team

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Development and translation of thiometallate sulfide donors using a porcine model of coronary occlusion and reperfusion nork Thomas W. Johnson, James Holt, Anna Kleyman, Shengyu Zhou, Eva Sammut, Vito Domenico Bruno, Charlotte Gaupp, Giacomo Stanzani, John Martin, Pietro Arina, Julia Deutsch, Raimondo Ascione, Mervyn Singer, Alex Dyson

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Taming hemoglobin chemistry—a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation nork Chris E. Cooper, Michelle Simons, Alex Dyson, Nélida Leiva Eriksson, Gary G. A. Silkstone, Natalie Syrett, Victoria Allen-Baume, Leif Bülow, Luca Ronda, Andrea Mozzarelli, Mervyn Singer, Brandon J. Reeder

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Study into the reversal of septic shock with landiolol (beta blockade): STRESS-L Study protocol for a randomised trial nork Daniel Francis McAuley, Simon Gates, Duncan Young, Nafisa Boota, Anthony C Gordon, Julian Bion, Dipesh Mistry, Ranjit Lall, Janet Lord, Gavin Perkins, Mervyn Singer, Tony Whitehouse, Scott Regan, Emma Skilton

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