Genetically engineered mouse models of Parkinson’s disease

Por Crabtree, Donna M, Zhang, Jianhua
Publicado em 2011

Dopamine and its metabolites in cathepsin D heterozygous mice before and after MPTP administration

Por Crabtree, Donna, Boyer-Guittaut, Michaël, Ouyang, Xiaosen, Fineberg, Naomi, Zhang, Jianhua
Publicado em 2013

ABCG2 AND MDR PROMOTE BRAINSTEM GLIOMAGENESIS AND LIMIT THE EFFICACY OF DASATINIB IN A DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MOUSE MODEL

Por Becher, Oren Josh, Mittapali, Rajendar, Chung, Alexander H., Crabtree, Donna, Elmquist, Willliam
Publicado em 2014

Overexpression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells(*)

Por Crabtree, Donna, Dodson, Matthew, Ouyang, Xiaosen, Boyer-Guittaut, Michaël, Liang, Qiuli, Ballestas, Mary E., Fineberg, Naomi, Zhang, Jianhua
Publicado em 2013

ABCG2 and ABCB1 limit the efficacy of dasatinib in a PDGF-B driven brainstem glioma model

Por Mittapalli, Rajendar K, Chung, Alexander H, Parrish, Karen E, Crabtree, Donna, Halvorson, Kyle G., Hu, Guo, Elmquist, William F, Becher, Oren J
Publicado no Mol Cancer Ther (2016)

Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis

Por Mercer, Jacob L., Argus, Joseph P., Crabtree, Donna M., Keenan, Melissa M., Wilks, Moses Q., Chi, Jen-Tsan Ashley, Bensinger, Steven J., Lavau, Catherine P., Wechsler, Daniel S.
Publicado no PLoS One (2015)

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

Por Halvorson, Kyle G., Barton, Kelly L., Schroeder, Kristin, Misuraca, Katherine L., Hoeman, Christine, Chung, Alex, Crabtree, Donna M., Cordero, Francisco J., Singh, Raj, Spasojevic, Ivan, Berlow, Noah, Pal, Ranadip, Becher, Oren J.
Publicado no PLoS One (2015)

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

Por Qiao, Liyan, Hamamichi, Shusei, Caldwell, Kim A, Caldwell, Guy A, Yacoubian, Talene A, Wilson, Scott, Xie, Zuo-Lei, Speake, Lisa D, Parks, Rachael, Crabtree, Donna, Liang, Qiuli, Crimmins, Stephen, Schneider, Lonnie, Uchiyama, Yasuo, Iwatsubo, Takeshi, Zhou, Yi, Peng, Lisheng, Lu, YouMing, Standaert, David G, Walls, Ken C, Shacka, John J, Roth, Kevin A, Zhang, Jianhua
Publicado em 2008