Nonglycosylated G-Protein Vaccine Protects against Homologous and Heterologous Respiratory Syncytial Virus (RSV) Challenge, while Glycosylated G Enhances RSV Lung Pathology and Cyt...

por Fuentes, Sandra, Coyle, Elizabeth M., Golding, Hana, Khurana, Surender
Publicado en J Virol (2015)

Antigenic Fingerprinting following Primary RSV Infection in Young Children Identifies Novel Antigenic Sites and Reveals Unlinked Evolution of Human Antibody Repertoires to Fusion a...

por Fuentes, Sandra, Coyle, Elizabeth M., Beeler, Judy, Golding, Hana, Khurana, Surender
Publicado en PLoS Pathog (2016)

Protective antigenic sites in respiratory syncytial virus G attachment protein outside the central conserved and cysteine noose domains

por Lee, Jeehyun, Klenow, Laura, Coyle, Elizabeth M., Golding, Hana, Khurana, Surender
Publicado en PLoS Pathog (2018)

Human Antibody Repertoire following Ebola Virus Infection and Vaccination

por Fuentes, Sandra, Ravichandran, Supriya, Coyle, Elizabeth M., Klenow, Laura, Khurana, Surender
Publicado en iScience (2020)

Antigenic Fingerprinting of Antibody Response in Humans following Exposure to Highly Pathogenic H7N7 Avian Influenza Virus: Evidence for Anti-PA-X Antibodies

por Khurana, Surender, Chung, Ka Yan, Coyle, Elizabeth M., Meijer, Adam, Golding, Hana
Publicado en J Virol (2016)

Heterologous Prime-Boost Vaccination with MF59-Adjuvanted H5 Vaccines Promotes Antibody Affinity Maturation towards the Hemagglutinin HA1 Domain and Broad H5N1 Cross-Clade Neutrali...

por Khurana, Surender, Coyle, Elizabeth M., Dimitrova, Milena, Castellino, Flora, Nicholson, Karl, Giudice, Giuseppe Del, Golding, Hana
Publicado 2014

Differential effects of phenethyl isothiocyanate and D,L-sulforaphane on Toll-like receptor 3 signaling

por Zhu, Jianzhong, Ghosh, Arundhati, Coyle, Elizabeth M., Lee, Joomin, Hahm, Eun-Ryeong, Singh, Shivendra V., Sarkar, Saumendra N.
Publicado 2013

Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

por Khurana, Surender, Hahn, Megan, Coyle, Elizabeth M., King, Lisa R., Lin, Tsai-Lien, Treanor, John, Sant, Andrea, Golding, Hana
Publicado en Nat Commun (2019)

Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits

por Ravichandran, Supriya, Coyle, Elizabeth M., Klenow, Laura, Tang, Juanjie, Grubbs, Gabrielle, Liu, Shufeng, Wang, Tony, Golding, Hana, Khurana, Surender
Publicado en Sci Transl Med (2020)

Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients

por Tang, Juanjie, Ravichandran, Supriya, Lee, Youri, Grubbs, Gabrielle, Coyle, Elizabeth M., Klenow, Laura, Genser, Hollie, Golding, Hana, Khurana, Surender
Publicado en Nat Commun (2021)

Oral Priming with Replicating Adenovirus Serotype 4 Followed by Subunit H5N1 Vaccine Boost Promotes Antibody Affinity Maturation and Expands H5N1 Cross-Clade Neutralization

por Khurana, Surender, Coyle, Elizabeth M., Manischewitz, Jody, King, Lisa R., Ishioka, Glenn, Alexander, Jeff, Smith, Jon, Gurwith, Marc, Golding, Hana
Publicado en PLoS One (2015)

AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization

por Khurana, Surender, Coyle, Elizabeth M., Manischewitz, Jody, King, Lisa R., Gao, Jin, Germain, Ronald N., Schwartzberg, Pamela L., Tsang, John S., Golding, Hana
Publicado en NPJ Vaccines (2018)

Longitudinal human antibody repertoire against complete viral proteome from Ebola virus survivor reveals protective sites for vaccine design

por Khurana, Surender, Ravichandran, Supriya, Hahn, Megan, Coyle, Elizabeth M., Stonier, Spencer W., Zak, Samantha E., Kindrachuk, Jason, Davey, Richard T., Dye, John M., Chertow, Daniel S.
Publicado en Cell Host Microbe (2020)

Antibody-dependent enhancement of influenza disease promoted by increase in hemagglutinin stem flexibility and virus fusion kinetics

por Winarski, Katie L., Tang, Juanjie, Klenow, Laura, Lee, Jeehyun, Coyle, Elizabeth M., Manischewitz, Jody, Turner, Hannah L., Takeda, Kazuyo, Ward, Andrew B., Golding, Hana, Khurana, Surender
Publicado en Proc Natl Acad Sci U S A (2019)

High-Affinity H7 Head and Stalk Domain–Specific Antibody Responses to an Inactivated Influenza H7N7 Vaccine After Priming With Live Attenuated Influenza Vaccine

por Halliley, Jessica L., Khurana, Surender, Krammer, Florian, Fitzgerald, Theresa, Coyle, Elizabeth M., Chung, Ka Yan, Baker, Steven F., Yang, Hongmei, Martínez-Sobrido, Luis, Treanor, John J., Subbarao, Kanta, Golding, Hana, Topham, David J., Sangster, Mark Y.
Publicado en J Infect Dis (2015)

Longitudinal antibody repertoire in “mild” versus “severe” COVID-19 patients reveals immune markers associated with disease severity and resolution

por Ravichandran, Supriya, Lee, Youri, Grubbs, Gabrielle, Coyle, Elizabeth M., Klenow, Laura, Akasaka, Osamu, Koga, Michiko, Adachi, Eisuke, Saito, Makoto, Nakachi, Ichiro, Ogura, Takayuki, Baba, Rie, Ito, Mutsumi, Kiso, Maki, Yasuhara, Atsuhiro, Yamada, Shinya, Sakai-Tagawa, Yuko, Iwatsuki-Horimoto, Kiyoko, Imai, Masaki, Yamayoshi, Seiya, Yotsuyanagi, Hiroshi, Kawaoka, Yoshihiro, Khurana, Surender
Publicado en Sci Adv (2021)

Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

por Dye, John M., Wu, Hua, Hooper, Jay W., Khurana, Surender, Kuehne, Ana I., Coyle, Elizabeth M., Ortiz, Ramon A., Fuentes, Sandra, Herbert, Andrew S., Golding, Hana, Bakken, Russell A., Brannan, Jennifer M., Kwilas, Steve A., Sullivan, Eddie J., Luke, Thomas C., Smith, Gale, Glenn, Gregory, Li, Wenfang, Ye, Ling, Yang, Chinglai, Compans, Richard W., Tripp, Ralph A., Jiao, Jin-an
Publicado en Sci Rep (2016)