Longitudinal human antibody repertoire against complete viral proteome from Ebola virus survivor reveals protective sites for vaccine design

Evolution of antibody repertoire against the Ebola virus (EBOV) proteome was characterized in an acutely infected patient receiving supportive care alone to elucidate virus-host interactions over time. Differential kinetics are observed for IgM/IgG/IgA epitope diversity, antibody binding, and affini...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Khurana, Surender, Ravichandran, Supriya, Hahn, Megan, Coyle, Elizabeth M., Stonier, Spencer W., Zak, Samantha E., Kindrachuk, Jason, Davey, Richard T., Dye, John M., Chertow, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071344/
https://ncbi.nlm.nih.gov/pubmed/32053790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.01.001
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