Longitudinal human antibody repertoire against complete viral proteome from Ebola virus survivor reveals protective sites for vaccine design

Evolution of antibody repertoire against the Ebola virus (EBOV) proteome was characterized in an acutely infected patient receiving supportive care alone to elucidate virus-host interactions over time. Differential kinetics are observed for IgM/IgG/IgA epitope diversity, antibody binding, and affini...

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Publicado en:Cell Host Microbe
Autores principales: Khurana, Surender, Ravichandran, Supriya, Hahn, Megan, Coyle, Elizabeth M., Stonier, Spencer W., Zak, Samantha E., Kindrachuk, Jason, Davey, Richard T., Dye, John M., Chertow, Daniel S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7071344/
https://ncbi.nlm.nih.gov/pubmed/32053790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.01.001
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