Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

Several vaccines are approved in the United States for seasonal influenza vaccination every year. Here we compare the impact of repeat influenza vaccination on hemagglutination inhibition (HI) titers, antibody binding and affinity maturation to individual hemagglutinin (HA) domains, HA1 and HA2, acr...

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Vydáno v:Nat Commun
Hlavní autoři: Khurana, Surender, Hahn, Megan, Coyle, Elizabeth M., King, Lisa R., Lin, Tsai-Lien, Treanor, John, Sant, Andrea, Golding, Hana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659679/
https://ncbi.nlm.nih.gov/pubmed/31350391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11296-5
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