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Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

Several vaccines are approved in the United States for seasonal influenza vaccination every year. Here we compare the impact of repeat influenza vaccination on hemagglutination inhibition (HI) titers, antibody binding and affinity maturation to individual hemagglutinin (HA) domains, HA1 and HA2, acr...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Khurana, Surender, Hahn, Megan, Coyle, Elizabeth M., King, Lisa R., Lin, Tsai-Lien, Treanor, John, Sant, Andrea, Golding, Hana
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659679/
https://ncbi.nlm.nih.gov/pubmed/31350391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11296-5
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