Insulin Substrate Receptor (IRS) proteins in normal and malignant hematopoiesis

por Machado-Neto, João Agostinho, Fenerich, Bruna Alves, Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Scopim-Ribeiro, Renata, Coelho-Silva, Juan Luiz, Traina, Fabiola
Publicado no Clinics (Sao Paulo) (2018)

Paclitaxel induces Stathmin 1 phosphorylation, microtubule stability and apoptosis in acute lymphoblastic leukemia cells

por Machado-Neto, João Agostinho, Rodrigues Alves, Ana Paula Nunes, Fernandes, Jaqueline Cristina, Coelho-Silva, Juan Luiz, Scopim-Ribeiro, Renata, Fenerich, Bruna Alves, da Silva, Fernanda Borges, Scheucher, Priscila Santos, Simões, Belinda Pinto, Rego, Eduardo Magalhães, Traina, Fabiola
Publicado no Heliyon (2017)

MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model

por Pereira-Martins, Diego A., Weinhäuser, Isabel, Coelho-Silva, Juan Luiz, França-Neto, Pedro L., Almeida, Luciana Y., Bianco, Thiago M., Silva, Cleide L., França, Rafael F., Traina, Fabiola, Rego, Eduardo M., Schuringa, Jan Jacob, Lucena-Araujo, Antonio R.
Publicado no Cell Death Dis (2021)

NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2(V617F)-positive myeloproliferative neoplasm cells

por Fenerich, Bruna Alves, Fernandes, Jaqueline Cristina, Rodrigues Alves, Ana Paula Nunes, Coelho-Silva, Juan Luiz, Scopim-Ribeiro, Renata, Scheucher, Priscila Santos, Eide, Christopher A., Tognon, Cristina E., Druker, Brian J., Rego, Eduardo Magalhães, Machado-Neto, João Agostinho, Traina, Fabiola
Publicado no Signal Transduct Target Ther (2020)

Metformin exerts multitarget antileukemia activity in JAK2(V617F)-positive myeloproliferative neoplasms

por Machado-Neto, João Agostinho, Fenerich, Bruna Alves, Scopim-Ribeiro, Renata, Eide, Christopher A., Coelho-Silva, Juan Luiz, Dechandt, Carlos Roberto Porto, Fernandes, Jaqueline Cristina, Rodrigues Alves, Ana Paula Nunes, Scheucher, Priscila Santos, Simões, Belinda Pinto, Alberici, Luciane Carla, de Figueiredo Pontes, Lorena Lôbo, Tognon, Cristina E., Druker, Brian J., Rego, Eduardo Magalhães, Traina, Fabiola
Publicado no Cell Death Dis (2018)

The application of an integrated clinical, cytogenetic, and molecular risk stratification for acute myeloid leukemia patients using a central laboratory in a Brazilian multicentric...

por Borges da Silva, Fernanda, de Figueiredo-Pontes, Lorena Lobo, Madeira, Maria Isabel Ayrosa, Corrêa de Araujo Koury, Luisa, Gouvêa de Lima, Ana Silvia, Santos Scheucher, Priscila, Coelho-Silva, Juan Luiz, Pagnano, Katia Borgia Barbosa, Pallota, Ronald, de Lourdes Chauffaille, Maria, Oltramari, Marcos Roberto Pedron, Bittencourt, Rosane Isabel, Higashi, Marcia, Bendlin, Rodrigo Miguel, Rodrigues Pereira Velloso, Elvira Deolinda, Lowenberg, Bob, Ganser, Arnold, Berliner, Nancy, Valk, Peter, Magalhães Rego, Eduardo, Traina, Fabiola
Publicado no Blood Adv (2017)