A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform

door Adamson-Small, Laura, Potter, Mark, Falk, Darin J, Cleaver, Brian, Byrne, Barry J, Clément, Nathalie
Gepubliceerd in Mol Ther Methods Clin Dev (2016)

IT-35 cGMP MANUFACTURING OF EX VIVO EXPANDED TUMOR-SPECIFIC T CELLS AND AMPLIFIED TUMOR RNA-PULSED DC VACCINES TARGETING GLIOBLASTOMA AND MEDULLOBLASTOMA

door Yegorov, Oleg, Dechkovskaia, Anjelika, Drake, Jeffery, Cleaver, Brian D., Clement, Nathalie, Huang, Jianping, Mitchell, Duane A.
Gepubliceerd in 2014

PDCT-08. TRACKING THE T CELL REPERTOIRE AFTER ADOPTIVE CELL THERAPY IN PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA

door Yegorov, Oleg, Yegorova, Yanina, Dechkovskaia, Anjelika, Cleaver, Brian, Clement, Nathalie, Slayton, William, Gururangan, Sridharan, Mitchell, Duane
Gepubliceerd in Neuro Oncol (2018)

ATIM-34. SINGLE-CELL RNA SEQUENCING REVEALS DYNAMIC IMMUNE RESPONSE CHANGES IN GLIOBLASTOMA PATIENT WITH DURABLE COMPLETE RESPONSE TO CMV PP65-LAMP RNA-PULSED DENDRITIC VACCINES

door Yegorov, Oleg, Yang, Changlin, Rahman, Maryam, Ghiaseddin, Ashley, Dechkovskaia, Anjelika, Cleaver, Brian, Hodik, Marcia, Amdur, Robert, Massini, Tara, Kresak, Jesse, Mitchell, Duane
Gepubliceerd in Neuro Oncol (2019)

Pompe disease gene therapy: neural manifestations require consideration of CNS directed therapy

door Byrne, Barry J., Fuller, David D., Smith, Barbara K., Clement, Nathalie, Coleman, Kirsten, Cleaver, Brian, Vaught, Lauren, Falk, Darin J., McCall, Angela, Corti, Manuela
Gepubliceerd in Ann Transl Med (2019)

A simplified purification protocol for recombinant adeno-associated virus vectors

door Potter, Mark, Lins, Bridget, Mietzsch, Mario, Heilbronn, Regine, Van Vliet, Kim, Chipman, Paul, Agbandje-McKenna, Mavis, Cleaver, Brian D, Clément, Nathalie, Byrne, Barry J, Zolotukhin, Sergei
Gepubliceerd in Mol Ther Methods Clin Dev (2014)

Evaluation of Readministration of a Recombinant Adeno-Associated Virus Vector Expressing Acid Alpha-Glucosidase in Pompe Disease: Preclinical to Clinical Planning

door Corti, Manuela, Cleaver, Brian, Clément, Nathalie, Conlon, Thomas J., Faris, Kaitlyn J., Wang, Gensheng, Benson, Janet, Tarantal, Alice F., Fuller, Davis, Herzog, Roland W., Byrne, Barry J.
Gepubliceerd in Hum Gene Ther Clin Dev (2015)

Phase I/II Trial of Adeno-Associated Virus–Mediated Alpha-Glucosidase Gene Therapy to the Diaphragm for Chronic Respiratory Failure in Pompe Disease: Initial Safety and Ventilatory...

door Smith, Barbara K., Collins, Shelley W., Conlon, Thomas J., Mah, Cathryn S., Lawson, Lee Ann, Martin, Anatole D., Fuller, David D., Cleaver, Brian D., Clément, Nathalie, Phillips, Dawn, Islam, Saleem, Dobjia, Nicole, Byrne, Barry J.
Gepubliceerd in 2013

Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of MERTK Associated Retinitis Pigmentosa

door Conlon, Thomas J., Deng, Wen-Tao, Erger, Kirsten, Cossette, Travis, Pang, Ji-jing, Ryals, Renee, Clément, Nathalie, Cleaver, Brian, McDoom, Issam, Boye, Shannon E., Peden, Marc C., Sherwood, Mark B., Abernathy, Corinne R., Alkuraya, Fowzan S., Boye, Sanford L., Hauswirth, William W.
Gepubliceerd in 2013

Pompe disease gene therapy

door Byrne, Barry J., Falk, Darin J., Pacak, Christina A., Nayak, Sushrusha, Herzog, Roland W., Elder, Melissa E., Collins, Shelley W., Conlon, Thomas J., Clement, Nathalie, Cleaver, Brian D., Cloutier, Denise A., Porvasnik, Stacy L., Islam, Saleem, Elmallah, Mai K., Martin, Anatole, Smith, Barbara K., Fuller, David D., Lawson, Lee Ann, Mah, Cathryn S.
Gepubliceerd in 2011