A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform

von Adamson-Small, Laura, Potter, Mark, Falk, Darin J, Cleaver, Brian, Byrne, Barry J, Clément, Nathalie
Veröffentlicht in Mol Ther Methods Clin Dev (2016)

IT-35 cGMP MANUFACTURING OF EX VIVO EXPANDED TUMOR-SPECIFIC T CELLS AND AMPLIFIED TUMOR RNA-PULSED DC VACCINES TARGETING GLIOBLASTOMA AND MEDULLOBLASTOMA

von Yegorov, Oleg, Dechkovskaia, Anjelika, Drake, Jeffery, Cleaver, Brian D., Clement, Nathalie, Huang, Jianping, Mitchell, Duane A.
Veröffentlicht 2014

PDCT-08. TRACKING THE T CELL REPERTOIRE AFTER ADOPTIVE CELL THERAPY IN PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA

von Yegorov, Oleg, Yegorova, Yanina, Dechkovskaia, Anjelika, Cleaver, Brian, Clement, Nathalie, Slayton, William, Gururangan, Sridharan, Mitchell, Duane
Veröffentlicht in Neuro Oncol (2018)

ATIM-34. SINGLE-CELL RNA SEQUENCING REVEALS DYNAMIC IMMUNE RESPONSE CHANGES IN GLIOBLASTOMA PATIENT WITH DURABLE COMPLETE RESPONSE TO CMV PP65-LAMP RNA-PULSED DENDRITIC VACCINES

von Yegorov, Oleg, Yang, Changlin, Rahman, Maryam, Ghiaseddin, Ashley, Dechkovskaia, Anjelika, Cleaver, Brian, Hodik, Marcia, Amdur, Robert, Massini, Tara, Kresak, Jesse, Mitchell, Duane
Veröffentlicht in Neuro Oncol (2019)

Pompe disease gene therapy: neural manifestations require consideration of CNS directed therapy

von Byrne, Barry J., Fuller, David D., Smith, Barbara K., Clement, Nathalie, Coleman, Kirsten, Cleaver, Brian, Vaught, Lauren, Falk, Darin J., McCall, Angela, Corti, Manuela
Veröffentlicht in Ann Transl Med (2019)

A simplified purification protocol for recombinant adeno-associated virus vectors

von Potter, Mark, Lins, Bridget, Mietzsch, Mario, Heilbronn, Regine, Van Vliet, Kim, Chipman, Paul, Agbandje-McKenna, Mavis, Cleaver, Brian D, Clément, Nathalie, Byrne, Barry J, Zolotukhin, Sergei
Veröffentlicht in Mol Ther Methods Clin Dev (2014)

Evaluation of Readministration of a Recombinant Adeno-Associated Virus Vector Expressing Acid Alpha-Glucosidase in Pompe Disease: Preclinical to Clinical Planning

von Corti, Manuela, Cleaver, Brian, Clément, Nathalie, Conlon, Thomas J., Faris, Kaitlyn J., Wang, Gensheng, Benson, Janet, Tarantal, Alice F., Fuller, Davis, Herzog, Roland W., Byrne, Barry J.
Veröffentlicht in Hum Gene Ther Clin Dev (2015)

Phase I/II Trial of Adeno-Associated Virus–Mediated Alpha-Glucosidase Gene Therapy to the Diaphragm for Chronic Respiratory Failure in Pompe Disease: Initial Safety and Ventilatory...

von Smith, Barbara K., Collins, Shelley W., Conlon, Thomas J., Mah, Cathryn S., Lawson, Lee Ann, Martin, Anatole D., Fuller, David D., Cleaver, Brian D., Clément, Nathalie, Phillips, Dawn, Islam, Saleem, Dobjia, Nicole, Byrne, Barry J.
Veröffentlicht 2013

Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of MERTK Associated Retinitis Pigmentosa

von Conlon, Thomas J., Deng, Wen-Tao, Erger, Kirsten, Cossette, Travis, Pang, Ji-jing, Ryals, Renee, Clément, Nathalie, Cleaver, Brian, McDoom, Issam, Boye, Shannon E., Peden, Marc C., Sherwood, Mark B., Abernathy, Corinne R., Alkuraya, Fowzan S., Boye, Sanford L., Hauswirth, William W.
Veröffentlicht 2013

Pompe disease gene therapy

von Byrne, Barry J., Falk, Darin J., Pacak, Christina A., Nayak, Sushrusha, Herzog, Roland W., Elder, Melissa E., Collins, Shelley W., Conlon, Thomas J., Clement, Nathalie, Cleaver, Brian D., Cloutier, Denise A., Porvasnik, Stacy L., Islam, Saleem, Elmallah, Mai K., Martin, Anatole, Smith, Barbara K., Fuller, David D., Lawson, Lee Ann, Mah, Cathryn S.
Veröffentlicht 2011