Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Por Clarke, Jonathan H., Irvine, Robin F.
Publicado em 2013

Enzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophrenia

Por Clarke, Jonathan H., Irvine, Robin F.
Publicado em 2013

Localization, regulation and function of Type II phosphatidylinositol 5-phosphate 4-kinases

Por Clarke, Jonathan H., Wang, Michael, Irvine, Robin F.
Publicado em 2010

Localization of phosphatidylinositol phosphate kinase IIγ in kidney to a membrane trafficking compartment within specialized cells of the nephron

Por Clarke, Jonathan H., Emson, Piers C., Irvine, Robin F.
Publicado em 2008

Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIγ in the mouse brain

Por Clarke, Jonathan H, Emson, Piers C, Irvine, Robin F
Publicado em 2009

Genomic tagging of endogenous Type IIβ Phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation

Por Richardson, Jonathan P., Wang, Minchuan, Clarke, Jonathan H., Patel, Ketan J., Irvine, R.F.
Publicado em 2007

Exploring phosphatidylinositol 5-phosphate 4-kinase function

Por Bulley, Simon J., Clarke, Jonathan H., Droubi, Alaa, Giudici, Maria-Luisa, Irvine, Robin F.
Publicado no Adv Biol Regul (2015)

Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development

Por Gupta, Amit, Toscano, Sarah, Trivedi, Deepti, Jones, David R., Mathre, Swarna, Clarke, Jonathan H., Divecha, Nullin, Raghu, Padinjat
Publicado em 2013

PI(5)P Regulates Autophagosome Biogenesis

Por Vicinanza, Mariella, Korolchuk, Viktor I., Ashkenazi, Avraham, Puri, Claudia, Menzies, Fiona M., Clarke, Jonathan H., Rubinsztein, David C.
Publicado no Mol Cell (2015)

Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform

Por Wang, Minchuan, Bond, Nicholas J., Letcher, Andrew J., Richardson, Jonathan P., Lilley, Kathryn S., Irvine, Robin F., Clarke, Jonathan H.
Publicado em 2010

In B cells, phosphatidylinositol 5-phosphate 4-kinase–α synthesizes PI(4,5)P(2) to impact mTORC2 and Akt signaling

Por Bulley, Simon J., Droubi, Alaa, Clarke, Jonathan H., Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Irvine, Robin F.
Publicado no Proc Natl Acad Sci U S A (2016)

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site

Por Clarke, Jonathan H., Giudici, Maria-Luisa, Burke, John E., Williams, Roger L., Maloney, David J., Marugan, Juan, Irvine, Robin F.
Publicado no Biochem J (2015)

DRL1, a Homolog of the Yeast TOT4/KTI12 Protein, Has a Function in Meristem Activity and Organ Growth in Plants

Por Nelissen, Hilde, Clarke, Jonathan H., De Block, Marc, De Block, Sabine, Vanderhaeghen, Rudy, Zielinski, Raymond E., Dyer, Tristan, Lust, Sofie, Inzé, Dirk, Van Lijsebettens, Mieke
Publicado em 2003