Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration

Por Clark, Simon J., Bishop, Paul N.
Publicado no J Clin Med (2014)

Age-related macular degeneration: genome-wide association studies to translation

Por Black, James R. M., Clark, Simon J.
Publicado no Genet Med (2016)

Point of care estimation of haemoglobin in neonates

Por Hinds, Lucy E, Brown, Caroline L, Clark, Simon J
Publicado em 2007

The Proteoglycan Glycomatrix: A Sugar Microenvironment Essential for Complement Regulation

Por Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Publicado em 2013

Complement factor H in host defense and immune evasion

Por Parente, Raffaella, Clark, Simon J., Inforzato, Antonio, Day, Anthony J.
Publicado no Cell Mol Life Sci (2016)

Enrichment of Bruch's Membrane from Human Donor Eyes

Por McHarg, Selina, Brace, Nicole, Bishop, Paul N., Clark, Simon J.
Publicado no J Vis Exp (2015)

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation

Por Langford-Smith, Alex, Day, Anthony J., Bishop, Paul N., Clark, Simon J.
Publicado no Front Immunol (2015)

Myocardial injury in infants ventilated on the paediatric intensive care unit: a case control study

Por Clark, Simon J, Eisenhut, Michael, Sidaras, Dorothea, Hancock, Stephen W, Newland, Paul, Thorburn, Kent
Publicado em 2006

The Role of Complement in Age-Related Macular Degeneration: Heparan Sulphate, a ZIP Code for Complement Factor H?

Por Langford-Smith, Alex, Keenan, Tiarnan D.L., Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Publicado em 2014

Genetic Variants in the Complement System Predisposing to Age-Related Macular Degeneration: A Review

Por Schramm, Elizabeth C., Clark, Simon J., Triebwasser, Michael P., Raychaudhuri, Soumya, Seddon, Johanna, Atkinson, John P.
Publicado em 2014

Identification of factor H-like protein 1 as the predominant complement regulator in Bruch’s membrane: implications for age-related macular degeneration

Por Clark, Simon J., Schmidt, Christoph Q., White, Anne M., Hakobyan, Svetlana, Morgan, B. Paul, Bishop, Paul N.
Publicado no J Immunol (2014)

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

Por Langford-Smith, Alex, Tilakaratna, Viranga, Lythgoe, Paul R., Clark, Simon J., Bishop, Paul N., Day, Anthony J.
Publicado no PLoS One (2016)

Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

Por Clark, Simon J., Perveen, Rahat, Hakobyan, Svetlana, Morgan, B. Paul, Sim, Robert B., Bishop, Paul N., Day, Anthony J.
Publicado em 2010

Mapping the Differential Distribution of Proteoglycan Core Proteins in the Adult Human Retina, Choroid, and Sclera

Por Keenan, Tiarnan D. L., Clark, Simon J., Unwin, Richard D., Ridge, Liam A., Day, Anthony J., Bishop, Paul N.
Publicado em 2012

Expression, purification, cocrystallization and preliminary crystallographic analysis of sucrose octasulfate/human complement regulator factor H SCRs 6–8

Por Prosser, Beverly E., Johnson, Steven, Roversi, Pietro, Clark, Simon J., Tarelli, Edward, Sim, Robert B., Day, Antony J., Lea, Susan M.
Publicado em 2007

Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions

Por Clark, Simon J., Ridge, Liam A., Herbert, Andrew P., Hakobyan, Svetlana, Mulloy, Barbara, Lennon, Rachel, Würzner, Reinhard, Morgan, B. Paul, Uhrín, Dusan, Bishop, Paul N., Day, Anthony J.
Publicado em 2013

Mapping the Differential Distribution of Glycosaminoglycans in the Adult Human Retina, Choroid, and Sclera

Por Clark, Simon J., Keenan, Tiarnan D. L., Fielder, Helen L., Collinson, Lisa J., Holley, Rebecca J., Merry, Catherine L. R., van Kuppevelt, Toin H., Day, Anthony J., Bishop, Paul N.
Publicado em 2011

Structural basis for complement factor H–linked age-related macular degeneration

Por Prosser, Beverly E., Johnson, Steven, Roversi, Pietro, Herbert, Andrew P., Blaum, Bärbel S., Tyrrell, Jess, Jowitt, Thomas A., Clark, Simon J., Tarelli, Edward, Uhrín, Dušan, Barlow, Paul N., Sim, Robert B., Day, Anthony J., Lea, Susan M.
Publicado em 2007

Development of a microtiter plate-based glycosaminoglycan array for the investigation of glycosaminoglycan-protein interactions

Por Marson, Andrew, Robinson, David E., Brookes, Patrick N., Mulloy, Barbara, Wiles, Michelle, Clark, Simon J., Fielder, Helen L., Collison, Lisa J., Cain, Stuart A., Kielty, Catherine M., McArthur, Sally, Buttle, David J., Short, Robert D., Whittle, Jason D., Day, Anthony J.
Publicado em 2009