Genetic Variants in the Complement System Predisposing to Age-Related Macular Degeneration: A Review

Age-related macular degeneration (AMD) is a major cause of visual impairment in the western world. It is characterized by the presence of lipoproteinaceous deposits (drusen) in the inner layers of the retina. Immunohistochemistry studies identified deposition of complement proteins in the drusen as...

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Bibliografiset tiedot
Päätekijät: Schramm, Elizabeth C., Clark, Simon J., Triebwasser, Michael P., Raychaudhuri, Soumya, Seddon, Johanna, Atkinson, John P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149817/
https://ncbi.nlm.nih.gov/pubmed/25034031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.06.032
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