Genetic Variants in the Complement System Predisposing to Age-Related Macular Degeneration: A Review

Age-related macular degeneration (AMD) is a major cause of visual impairment in the western world. It is characterized by the presence of lipoproteinaceous deposits (drusen) in the inner layers of the retina. Immunohistochemistry studies identified deposition of complement proteins in the drusen as...

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Main Authors: Schramm, Elizabeth C., Clark, Simon J., Triebwasser, Michael P., Raychaudhuri, Soumya, Seddon, Johanna, Atkinson, John P.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149817/
https://ncbi.nlm.nih.gov/pubmed/25034031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2014.06.032
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