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Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration

PURPOSE: Age-related macular degeneration (AMD) has a substantial genetic risk component, as evidenced by the risk from common genetic variants uncovered in the first genome-wide association studies. More recently, it has become apparent that rare genetic variants also play an independent role in AM...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Triebwasser, Michael P., Roberson, Elisha D. O., Yu, Yi, Schramm, Elizabeth C., Wagner, Erin K., Raychaudhuri, Soumya, Seddon, Johanna M., Atkinson, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627248/
https://ncbi.nlm.nih.gov/pubmed/26501415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17432
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