The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment

Por Pennock, Gregory K., Chow, Laura Q.M.
Publicado no Oncologist (2015)

Systemic therapy of brain metastases: non–small cell lung cancer, breast cancer, and melanoma

Por Chamberlain, Marc C., Baik, Christina S., Gadi, Vijayakrishna K., Bhatia, Shailender, Chow, Laura Q.M.
Publicado no Neuro Oncol (2017)

Immuno-oncology Trial Endpoints: Capturing Clinically Meaningful Activity

Por Anagnostou, Valsamo, Yarchoan, Mark, Hansen, Aaron R., Wang, Hao, Verde, Franco, Sharon, Elad, Collyar, Deborah, Chow, Laura Q.M., Forde, Patrick M.
Publicado no Clin Cancer Res (2017)

Immuno-oncology Clinical Trial Design: Limitations, Challenges, and Opportunities

Por Baik, Christina S., Rubin, Eric H., Forde, Patrick M., Mehnert, Janice M., Collyar, Deborah, Butler, Marcus O., Dixon, Erica L., Chow, Laura Q.M.
Publicado no Clin Cancer Res (2017)

Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study

Por Nanda, Rita, Chow, Laura Q.M., Dees, E. Claire, Berger, Raanan, Gupta, Shilpa, Geva, Ravit, Pusztai, Lajos, Pathiraja, Kumudu, Aktan, Gursel, Cheng, Jonathan D., Karantza, Vassiliki, Buisseret, Laurence
Publicado no J Clin Oncol (2016)

A Phase I Clinical Trial of AZD1775 in Combination With Neoadjuvant Weekly Docetaxel and Cisplatin Before Definitive Therapy in Head and Neck Squamous Cell Carcinoma

Por Méndez, Eduardo, Rodriguez, Cristina P., Kao, Michael C., Raju, Sharat, Diab, Ahmed, Harbison, R. Alex, Konnick, Eric Q., Mugundu, Ganesh M., Santana-Davila, Rafael, Martins, Renato, Futran, Neal D., Chow, Laura Q.M.
Publicado no Clin Cancer Res (2018)

Phase I Pharmacologic and Biologic Study of Ramucirumab (IMC-1121B), a Fully Human Immunoglobulin G(1) Monoclonal Antibody Targeting the Vascular Endothelial Growth Factor Receptor...

Por Spratlin, Jennifer L., Cohen, Roger B., Eadens, Matthew, Gore, Lia, Camidge, D. Ross, Diab, Sami, Leong, Stephen, O'Bryant, Cindy, Chow, Laura Q.M., Serkova, Natalie J., Meropol, Neal J., Lewis, Nancy L., Chiorean, E. Gabriela, Fox, Floyd, Youssoufian, Hagop, Rowinsky, Eric K., Eckhardt, S. Gail
Publicado em 2010

Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non—Small-Cell Lung Cancer and Activating Epidermal Growth Factor...

Por Leighl, Natasha B., Rizvi, Naiyer A., de Lima, Lopes Gilberto, Arpornwirat, Wichit, Rudin, Charles M., Chiappori, Alberto A., Ahn, Myung-Ju, Chow, Laura Q.M., Bazhenova, Lyudmila, Dechaphunkul, Arunee, Sunpaweravong, Patrapim, Eaton, Keith, Chen, Jihong, Medley, Sonja, Poondru, Srinivasu, Singh, Margaret, Steinberg, Joyce, Juergens, Rosalyn A., Gadgeel, Shirish M.
Publicado no Clin Lung Cancer (2016)

BM-32 CERITINIB (LDK378) FOR TREATMENT OF PATIENTS WITH ALK-REARRANGED (ALK+) NON-SMALL CELL LUNG CANCER (NSCLC) AND BRAIN METASTASES (BM) IN THE ASCEND-1 TRIAL

Por Shaw, Alice, Mehra, Ranee, Tan, Daniel S.W., Felip, Enriqueta, Chow, Laura Q.M., Ross Camidge, D., Vansteenkiste, Johan, Sharma, Sunil, De Pas, Tommaso, Riely, Gregory J., Solomon, Benjamin J., Wolf, Juergen, Thomas, Michael, Schuler, Martin, Liu, Geoffrey, Santoro, Armando, Geraldes, Margarida, Sen, Paramita, Boral, Anthony J., Yovine, Alejandro, Kim, Dong-Wan
Publicado em 2014

Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 E...

Por Chow, Laura Q.M., Haddad, Robert, Gupta, Shilpa, Mahipal, Amit, Mehra, Ranee, Tahara, Makoto, Berger, Raanan, Eder, Joseph Paul, Burtness, Barbara, Lee, Se-Hoon, Keam, Bhumsuk, Kang, Hyunseok, Muro, Kei, Weiss, Jared, Geva, Ravit, Lin, Chia-Chi, Chung, Hyun Cheol, Meister, Amy, Dolled-Filhart, Marisa, Pathiraja, Kumudu, Cheng, Jonathan D., Seiwert, Tanguy Y.
Publicado no J Clin Oncol (2016)

Ceritinib in ALK-Rearranged Non–Small-Cell Lung Cancer

Por Shaw, Alice T., Kim, Dong-Wan, Mehra, Ranee, Tan, Daniel S.W., Felip, Enriqueta, Chow, Laura Q.M., Camidge, D. Ross, Vansteenkiste, Johan, Sharma, Sunil, De Pas, Tommaso, Riely, Gregory J., Solomon, Benjamin J., Wolf, Juergen, Thomas, Michael, Schuler, Martin, Liu, Geoffrey, Santoro, Armando, Lau, Yvonne Y., Goldwasser, Meredith, Boral, Anthony L., Engelman, Jeffrey A.
Publicado em 2014

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

Por Brahmer, Julie R., Tykodi, Scott S., Chow, Laura Q.M., Hwu, Wen-Jen, Topalian, Suzanne L., Hwu, Patrick, Drake, Charles G., Camacho, Luis H., Kauh, John, Odunsi, Kunle, Pitot, Henry C., Hamid, Omid, Bhatia, Shailender, Martins, Renato, Eaton, Keith, Chen, Shuming, Salay, Theresa M., Alaparthy, Suresh, Grosso, Joseph F., Korman, Alan J., Parker, Susan M., Agrawal, Shruti, Goldberg, Stacie M., Pardoll, Drew M., Gupta, Ashok, Wigginton, Jon M.
Publicado em 2012

Small Cell Lung Cancer: Clinical Practice Guidelines in Oncology

Por Kalemkerian, Gregory P., Akerley, Wallace, Bogner, Paul, Borghaei, Hossein, Chow, Laura QM, Downey, Robert J., Gandhi, Leena, Ganti, Apar Kishor P., Govindan, Ramaswamy, Grecula, John C., Hayman, James, Heist, Rebecca Suk, Horn, Leora, Jahan, Thierry, Koczywas, Marianna, Loo, Billy W., Merritt, Robert E., Moran, Cesar A., Niell, Harvey B., O’Malley, Janis, Patel, Jyoti D., Ready, Neal, Rudin, Charles M., Williams, Charles C., Gregory, Kristina, Hughes, Miranda
Publicado em 2013

Phase II Trial of Atezolizumab As First-Line or Subsequent Therapy for Patients With Programmed Death-Ligand 1–Selected Advanced Non–Small-Cell Lung Cancer (BIRCH)

Por Peters, Solange, Gettinger, Scott, Johnson, Melissa L., Jänne, Pasi A., Garassino, Marina C., Christoph, Daniel, Toh, Chee Keong, Rizvi, Naiyer A., Chaft, Jamie E., Carcereny Costa, Enric, Patel, Jyoti D., Chow, Laura Q.M., Koczywas, Marianna, Ho, Cheryl, Früh, Martin, van den Heuvel, Michel, Rothenstein, Jeffrey, Reck, Martin, Paz-Ares, Luis, Shepherd, Frances A., Kurata, Takayasu, Li, Zhengrong, Qiu, Jiaheng, Kowanetz, Marcin, Mocci, Simonetta, Shankar, Geetha, Sandler, Alan, Felip, Enriqueta
Publicado no J Clin Oncol (2017)