RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

door Chan, Ho Yin Edwin
Gepubliceerd in Front Cell Neurosci (2014)

A mechanism for reversible mesoscopic aggregation in liquid solutions

door Chan, Ho Yin, Lubchenko, Vassiliy
Gepubliceerd in Nat Commun (2019)

Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases

door Koon, Alex C., Chan, Ho Yin Edwin
Gepubliceerd in Front Cell Neurosci (2017)

Transcriptional dysregulation in neurodegenerative diseases: who tipped the balance of Yin Yang 1 in the brain?

door Chen, Zhefan Stephen, Chan, Ho Yin Edwin
Gepubliceerd in Neural Regen Res (2019)

Anisotropy of the Coulomb Interaction between Folded Proteins: Consequences for Mesoscopic Aggregation of Lysozyme

door Chan, Ho Yin, Lankevich, Vladimir, Vekilov, Peter G., Lubchenko, Vassiliy
Gepubliceerd in 2012

Lack of Dependence of the Sizes of the Mesoscopic Protein Clusters on Electrostatics

door Vorontsova, Maria A., Chan, Ho Yin, Lubchenko, Vassiliy, Vekilov, Peter G.
Gepubliceerd in Biophys J (2015)

A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3

door Chen, Zhefan Stephen, Huang, Xiaoying, Talbot, Kevin, Chan, Ho Yin Edwin
Gepubliceerd in Cell Death Dis (2021)

Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

door Chen, Zhefan Stephen, Lin, Xiao, Chan, Ting-Fung, Chan, Ho Yin Edwin
Gepubliceerd in Aging (Albany NY) (2021)

COVID-19, community response, public policy, and travel patterns: A tale of Hong Kong

door Chan, Ho-Yin, Chen, Anthony, Ma, Wei, Sze, Nang-Ngai, Liu, Xintao
Gepubliceerd in Transp Policy (Oxf) (2021)

Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor

door Li, Li, Ng, Nelson Ka Lam, Koon, Alex Chun, Chan, Ho Yin Edwin
Gepubliceerd in J Biol Chem (2017)

Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles

door Kim, Ma Rie, Feng, Teng, Zhang, Qian, Chan, Ho Yin Edwin, Chau, Ying
Gepubliceerd in Polymers (Basel) (2019)

The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway

door Chan, Chak-Ming, Ma, Cheuk-Wing, Chan, Wood-Yee, Chan, Ho Yin Edwin
Gepubliceerd in Arch Biochem Biophys (2007)

Polycrystalline-Diamond MEMS Biosensors Including Neural Microelectrode-Arrays

door Varney, Michael W., Aslam, Dean M., Janoudi, Abed, Chan, Ho-Yin, Wang, Donna H.
Gepubliceerd in Biosensors (Basel) (2011)

Isolation and Identification of a Novel Anti-protein Aggregation Activity of Lignin-Carbohydrate Complex From Chionanthus retusus Leaves

door Pei, Wenhui, Chen, Zhefan Stephen, Chan, Ho Yin Edwin, Zheng, Liming, Liang, Chen, Huang, Caoxing
Gepubliceerd in Front Bioeng Biotechnol (2020)

CAG expansion induces nucleolar stress in polyglutamine diseases

door Tsoi, Ho, Lau, Terrence Chi-Kong, Tsang, Suk-Ying, Lau, Kwok-Fai, Chan, Ho Yin Edwin
Gepubliceerd in 2012

Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

door Xu, Zheng, Chau, So Fun, Lam, Kwok Ho, Chan, Ho Yin, Ng, Tzi Bun, Au, Shannon W. N.
Gepubliceerd in 2006

Improving Atomic Force Microscopy Imaging by a Direct Inverse Asymmetric PI Hysteresis Model

door Wang, Dong, Yu, Peng, Wang, Feifei, Chan, Ho-Yin, Zhou, Lei, Dong, Zaili, Liu, Lianqing, Li, Wen Jung
Gepubliceerd in Sensors (Basel) (2015)

GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease

door Vivien Chiu, Wai Yin, Koon, Alex Chun, Ki Ngo, Jacky Chi, Edwin Chan, Ho Yin, Lau, Kwok-Fai
Gepubliceerd in Oncotarget (2017)

Whole-genome sequencing of two probands with hereditary spastic paraplegia reveals novel splice-donor region variant and known pathogenic variant in SPG11

door Yu, Allen Chi-Shing, Chan, Anne Yin-Yan, Au, Wing Chi, Shen, Yun, Chan, Ting Fung, Chan, Ho-Yin Edwin
Gepubliceerd in Cold Spring Harb Mol Case Stud (2016)

A Peptidylic Inhibitor for Neutralizing (r)(GGGGCC)(exp)-Associated Neurodegeneration in C9ALS-FTD

door Zhang, Qian, An, Ying, Chen, Zhefan Stephen, Koon, Alex Chun, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Gepubliceerd in Mol Ther Nucleic Acids (2019)