Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

SUMO (small ubiquitin-related modifier)-specific proteases catalyse the maturation and de-conjugation processes of the sumoylation pathway and modulate various cellular responses including nuclear metabolism and cell cycle progression. The active-site cysteine residue is conserved among all known SU...

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Bibliografiska uppgifter
Huvudupphovsmän: Xu, Zheng, Chau, So Fun, Lam, Kwok Ho, Chan, Ho Yin, Ng, Tzi Bun, Au, Shannon W. N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2006
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559472/
https://ncbi.nlm.nih.gov/pubmed/16712526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060526
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