RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

di Chan, Ho Yin Edwin
Pubblicato in Front Cell Neurosci (2014)

A mechanism for reversible mesoscopic aggregation in liquid solutions

di Chan, Ho Yin, Lubchenko, Vassiliy
Pubblicato in Nat Commun (2019)

Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases

di Koon, Alex C., Chan, Ho Yin Edwin
Pubblicato in Front Cell Neurosci (2017)

Transcriptional dysregulation in neurodegenerative diseases: who tipped the balance of Yin Yang 1 in the brain?

di Chen, Zhefan Stephen, Chan, Ho Yin Edwin
Pubblicato in Neural Regen Res (2019)

Anisotropy of the Coulomb Interaction between Folded Proteins: Consequences for Mesoscopic Aggregation of Lysozyme

di Chan, Ho Yin, Lankevich, Vladimir, Vekilov, Peter G., Lubchenko, Vassiliy
Pubblicazione 2012

Lack of Dependence of the Sizes of the Mesoscopic Protein Clusters on Electrostatics

di Vorontsova, Maria A., Chan, Ho Yin, Lubchenko, Vassiliy, Vekilov, Peter G.
Pubblicato in Biophys J (2015)

A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3

di Chen, Zhefan Stephen, Huang, Xiaoying, Talbot, Kevin, Chan, Ho Yin Edwin
Pubblicato in Cell Death Dis (2021)

Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

di Chen, Zhefan Stephen, Lin, Xiao, Chan, Ting-Fung, Chan, Ho Yin Edwin
Pubblicato in Aging (Albany NY) (2021)

COVID-19, community response, public policy, and travel patterns: A tale of Hong Kong

di Chan, Ho-Yin, Chen, Anthony, Ma, Wei, Sze, Nang-Ngai, Liu, Xintao
Pubblicato in Transp Policy (Oxf) (2021)

Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor

di Li, Li, Ng, Nelson Ka Lam, Koon, Alex Chun, Chan, Ho Yin Edwin
Pubblicato in J Biol Chem (2017)

Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles

di Kim, Ma Rie, Feng, Teng, Zhang, Qian, Chan, Ho Yin Edwin, Chau, Ying
Pubblicato in Polymers (Basel) (2019)

The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway

di Chan, Chak-Ming, Ma, Cheuk-Wing, Chan, Wood-Yee, Chan, Ho Yin Edwin
Pubblicato in Arch Biochem Biophys (2007)

Polycrystalline-Diamond MEMS Biosensors Including Neural Microelectrode-Arrays

di Varney, Michael W., Aslam, Dean M., Janoudi, Abed, Chan, Ho-Yin, Wang, Donna H.
Pubblicato in Biosensors (Basel) (2011)

Isolation and Identification of a Novel Anti-protein Aggregation Activity of Lignin-Carbohydrate Complex From Chionanthus retusus Leaves

di Pei, Wenhui, Chen, Zhefan Stephen, Chan, Ho Yin Edwin, Zheng, Liming, Liang, Chen, Huang, Caoxing
Pubblicato in Front Bioeng Biotechnol (2020)

CAG expansion induces nucleolar stress in polyglutamine diseases

di Tsoi, Ho, Lau, Terrence Chi-Kong, Tsang, Suk-Ying, Lau, Kwok-Fai, Chan, Ho Yin Edwin
Pubblicazione 2012

Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

di Xu, Zheng, Chau, So Fun, Lam, Kwok Ho, Chan, Ho Yin, Ng, Tzi Bun, Au, Shannon W. N.
Pubblicazione 2006

Improving Atomic Force Microscopy Imaging by a Direct Inverse Asymmetric PI Hysteresis Model

di Wang, Dong, Yu, Peng, Wang, Feifei, Chan, Ho-Yin, Zhou, Lei, Dong, Zaili, Liu, Lianqing, Li, Wen Jung
Pubblicato in Sensors (Basel) (2015)

GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease

di Vivien Chiu, Wai Yin, Koon, Alex Chun, Ki Ngo, Jacky Chi, Edwin Chan, Ho Yin, Lau, Kwok-Fai
Pubblicato in Oncotarget (2017)

Whole-genome sequencing of two probands with hereditary spastic paraplegia reveals novel splice-donor region variant and known pathogenic variant in SPG11

di Yu, Allen Chi-Shing, Chan, Anne Yin-Yan, Au, Wing Chi, Shen, Yun, Chan, Ting Fung, Chan, Ho-Yin Edwin
Pubblicato in Cold Spring Harb Mol Case Stud (2016)

A Peptidylic Inhibitor for Neutralizing (r)(GGGGCC)(exp)-Associated Neurodegeneration in C9ALS-FTD

di Zhang, Qian, An, Ying, Chen, Zhefan Stephen, Koon, Alex Chun, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Pubblicato in Mol Ther Nucleic Acids (2019)