RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

per Chan, Ho Yin Edwin
Publicat a Front Cell Neurosci (2014)

A mechanism for reversible mesoscopic aggregation in liquid solutions

per Chan, Ho Yin, Lubchenko, Vassiliy
Publicat a Nat Commun (2019)

Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases

per Koon, Alex C., Chan, Ho Yin Edwin
Publicat a Front Cell Neurosci (2017)

Transcriptional dysregulation in neurodegenerative diseases: who tipped the balance of Yin Yang 1 in the brain?

per Chen, Zhefan Stephen, Chan, Ho Yin Edwin
Publicat a Neural Regen Res (2019)

Anisotropy of the Coulomb Interaction between Folded Proteins: Consequences for Mesoscopic Aggregation of Lysozyme

per Chan, Ho Yin, Lankevich, Vladimir, Vekilov, Peter G., Lubchenko, Vassiliy
Publicat 2012

Lack of Dependence of the Sizes of the Mesoscopic Protein Clusters on Electrostatics

per Vorontsova, Maria A., Chan, Ho Yin, Lubchenko, Vassiliy, Vekilov, Peter G.
Publicat a Biophys J (2015)

A fine balance between Prpf19 and Exoc7 in achieving degradation of aggregated protein and suppression of cell death in spinocerebellar ataxia type 3

per Chen, Zhefan Stephen, Huang, Xiaoying, Talbot, Kevin, Chan, Ho Yin Edwin
Publicat a Cell Death Dis (2021)

Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

per Chen, Zhefan Stephen, Lin, Xiao, Chan, Ting-Fung, Chan, Ho Yin Edwin
Publicat a Aging (Albany NY) (2021)

COVID-19, community response, public policy, and travel patterns: A tale of Hong Kong

per Chan, Ho-Yin, Chen, Anthony, Ma, Wei, Sze, Nang-Ngai, Liu, Xintao
Publicat a Transp Policy (Oxf) (2021)

Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor

per Li, Li, Ng, Nelson Ka Lam, Koon, Alex Chun, Chan, Ho Yin Edwin
Publicat a J Biol Chem (2017)

Co-Encapsulation and Co-Delivery of Peptide Drugs via Polymeric Nanoparticles

per Kim, Ma Rie, Feng, Teng, Zhang, Qian, Chan, Ho Yin Edwin, Chau, Ying
Publicat a Polymers (Basel) (2019)

The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway

per Chan, Chak-Ming, Ma, Cheuk-Wing, Chan, Wood-Yee, Chan, Ho Yin Edwin
Publicat a Arch Biochem Biophys (2007)

Polycrystalline-Diamond MEMS Biosensors Including Neural Microelectrode-Arrays

per Varney, Michael W., Aslam, Dean M., Janoudi, Abed, Chan, Ho-Yin, Wang, Donna H.
Publicat a Biosensors (Basel) (2011)

Isolation and Identification of a Novel Anti-protein Aggregation Activity of Lignin-Carbohydrate Complex From Chionanthus retusus Leaves

per Pei, Wenhui, Chen, Zhefan Stephen, Chan, Ho Yin Edwin, Zheng, Liming, Liang, Chen, Huang, Caoxing
Publicat a Front Bioeng Biotechnol (2020)

CAG expansion induces nucleolar stress in polyglutamine diseases

per Tsoi, Ho, Lau, Terrence Chi-Kong, Tsang, Suk-Ying, Lau, Kwok-Fai, Chan, Ho Yin Edwin
Publicat 2012

Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

per Xu, Zheng, Chau, So Fun, Lam, Kwok Ho, Chan, Ho Yin, Ng, Tzi Bun, Au, Shannon W. N.
Publicat 2006

Improving Atomic Force Microscopy Imaging by a Direct Inverse Asymmetric PI Hysteresis Model

per Wang, Dong, Yu, Peng, Wang, Feifei, Chan, Ho-Yin, Zhou, Lei, Dong, Zaili, Liu, Lianqing, Li, Wen Jung
Publicat a Sensors (Basel) (2015)

GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer’s disease

per Vivien Chiu, Wai Yin, Koon, Alex Chun, Ki Ngo, Jacky Chi, Edwin Chan, Ho Yin, Lau, Kwok-Fai
Publicat a Oncotarget (2017)

Whole-genome sequencing of two probands with hereditary spastic paraplegia reveals novel splice-donor region variant and known pathogenic variant in SPG11

per Yu, Allen Chi-Shing, Chan, Anne Yin-Yan, Au, Wing Chi, Shen, Yun, Chan, Ting Fung, Chan, Ho-Yin Edwin
Publicat a Cold Spring Harb Mol Case Stud (2016)

A Peptidylic Inhibitor for Neutralizing (r)(GGGGCC)(exp)-Associated Neurodegeneration in C9ALS-FTD

per Zhang, Qian, An, Ying, Chen, Zhefan Stephen, Koon, Alex Chun, Lau, Kwok-Fai, Ngo, Jacky Chi Ki, Chan, Ho Yin Edwin
Publicat a Mol Ther Nucleic Acids (2019)