R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment

Por Carroll, Robert J., Bastarache, Lisa, Denny, Joshua C.
Publicado em 2014

Naïve Electronic Health Record Phenotype Identification for Rheumatoid Arthritis

Por Carroll, Robert J., Eyler, Anne E., Denny, Joshua C.
Publicado em 2011

Intelligent Use and Clinical Benefits of Electronic Health Records in Rheumatoid Arthritis

Por Carroll, Robert J., Eyler, Anne E., Denny, Joshua C.
Publicado no Expert Rev Clin Immunol (2015)

Interaction of Phosphatidylcholine with β-lactoglobulind

Por Brown, Eleanor M., Sampugna, Joseph, Pfeffer, Philip E., Carroll, Robert J.
Publicado em 1982

Phenome-Wide Association Study of Rheumatoid Arthritis Subgroups Identifies Association between Seronegative Disease and Fibromyalgia

Por Doss, Jayanth, Mo, Huan, Carroll, Robert J., Crofford, Leslie J., Denny, Joshua C.
Publicado no Arthritis Rheumatol (2017)

Developing Electronic Health Record Algorithms that Accurately Identify Patients with Systemic Lupus Erythematosus

Por Barnado, April, Casey, Carolyn, Carroll, Robert J., Wheless, Lee, Denny, Joshua C., Crofford, Leslie J.
Publicado no Arthritis Care Res (Hoboken) (2017)

Applying active learning to high-throughput phenotyping algorithms for electronic health records data

Por Chen, Yukun, Carroll, Robert J, Hinz, Eugenia R McPeek, Shah, Anushi, Eyler, Anne E, Denny, Joshua C, Xu, Hua
Publicado em 2013

A gene-based association method for mapping traits using reference transcriptome data

Por Gamazon, Eric R., Wheeler, Heather E., Shah, Kaanan P., Mozaffari, Sahar V., Aquino-Michaels, Keston, Carroll, Robert J., Eyler, Anne E., Denny, Joshua C., Nicolae, Dan L., Cox, Nancy J., Kyung Im, Hae
Publicado no Nat Genet (2015)

Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals

Por Teixeira, Pedro L, Wei, Wei-Qi, Cronin, Robert M, Mo, Huan, VanHouten, Jacob P, Carroll, Robert J, LaRose, Eric, Bastarache, Lisa A, Rosenbloom, S. Trent, Edwards, Todd L, Roden, Dan M, Lasko, Thomas A, Dart, Richard A, Nikolai, Anne M, Peissig, Peggy L, Denny, Joshua C
Publicado no J Am Med Inform Assoc (2017)

Portability of an algorithm to identify rheumatoid arthritis in electronic health records

Por Carroll, Robert J, Thompson, Will K, Eyler, Anne E, Mandelin, Arthur M, Cai, Tianxi, Zink, Raquel M, Pacheco, Jennifer A, Boomershine, Chad S, Lasko, Thomas A, Xu, Hua, Karlson, Elizabeth W, Perez, Raul G, Gainer, Vivian S, Murphy, Shawn N, Ruderman, Eric M, Pope, Richard M, Plenge, Robert M, Kho, Abel Ngo, Liao, Katherine P, Denny, Joshua C
Publicado em 2012

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

Por Denny, Joshua C, Bastarache, Lisa, Ritchie, Marylyn D, Carroll, Robert J, Zink, Raquel, Mosley, Jonathan D, Field, Julie R, Pulley, Jill M, Ramirez, Andrea H, Bowton, Erica, Basford, Melissa A, Carrell, David S, Peissig, Peggy L, Kho, Abel N, Pacheco, Jennifer A, Rasmussen, Luke V, Crosslin, David R, Crane, Paul K, Pathak, Jyotishman, Bielinski, Suzette J, Pendergrass, Sarah A, Xu, Hua, Hindorff, Lucia A, Li, Rongling, Manolio, Teri A, Chute, Christopher G, Chisholm, Rex L, Larson, Eric B, Jarvik, Gail P, Brilliant, Murray H, McCarty, Catherine A, Kullo, Iftikhar J, Haines, Jonathan L, Crawford, Dana C, Masys, Daniel R, Roden, Dan M
Publicado em 2013

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

Por Cronin, Robert M., Field, Julie R., Bradford, Yuki, Shaffer, Christian M., Carroll, Robert J., Mosley, Jonathan D., Bastarache, Lisa, Edwards, Todd L., Hebbring, Scott J., Lin, Simon, Hindorff, Lucia A., Crane, Paul K., Pendergrass, Sarah A., Ritchie, Marylyn D., Crawford, Dana C., Pathak, Jyotishman, Bielinski, Suzette J., Carrell, David S., Crosslin, David R., Ledbetter, David H., Carey, David J., Tromp, Gerard, Williams, Marc S., Larson, Eric B., Jarvik, Gail P., Peissig, Peggy L., Brilliant, Murray H., McCarty, Catherine A., Chute, Christopher G., Kullo, Iftikhar J., Bottinger, Erwin, Chisholm, Rex, Smith, Maureen E., Roden, Dan M., Denny, Joshua C.
Publicado em 2014

Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene

Por Okada, Yukinori, Diogo, Dorothee, Greenberg, Jeffrey D., Mouassess, Faten, Achkar, Walid A. L., Fulton, Robert S., Denny, Joshua C., Gupta, Namrata, Mirel, Daniel, Gabriel, Stacy, Li, Gang, Kremer, Joel M., Pappas, Dimitrios A., Carroll, Robert J., Eyler, Anne E., Trynka, Gosia, Stahl, Eli A., Cui, Jing, Saxena, Richa, Coenen, Marieke J. H., Guchelaar, Henk-Jan, Huizinga, Tom W. J., Dieudé, Philippe, Mariette, Xavier, Barton, Anne, Canhão, Helena, Fonseca, João E., de Vries, Niek, Tak, Paul P., Moreland, Larry W., Bridges, S. Louis, Miceli-Richard, Corinne, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Raj, Towfique, De Jager, Philip L., Raychaudhuri, Soumya, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Siminovitch, Katherine A., Gregersen, Peter K., Mardis, Elaine R., Arayssi, Thurayya, Kazkaz, Layla A., Plenge, Robert M.
Publicado em 2014

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Por Okada, Yukinori, Wu, Di, Trynka, Gosia, Raj, Towfique, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Yoshida, Shinji, Graham, Robert R., Manoharan, Arun, Ortmann, Ward, Bhangale, Tushar, Denny, Joshua C., Carroll, Robert J., Eyler, Anne E., Greenberg, Jeffrey D., Kremer, Joel M., Pappas, Dimitrios A., Jiang, Lei, Yin, Jian, Ye, Lingying, Su, Ding-Feng, Yang, Jian, Xie, Gang, Keystone, Ed, Westra, Harm-Jan, Esko, Tõnu, Metspalu, Andres, Zhou, Xuezhong, Gupta, Namrata, Mirel, Daniel, Stahl, Eli A., Diogo, Dorothée, Cui, Jing, Liao, Katherine, Guo, Michael H., Myouzen, Keiko, Kawaguchi, Takahisa, Coenen, Marieke J.H., van Riel, Piet L.C.M., van de Laar, Mart A.F.J., Guchelaar, Henk-Jan, Huizinga, Tom W.J., Dieudé, Philippe, Mariette, Xavier, Bridges, S. Louis, Zhernakova, Alexandra, Toes, Rene E.M., Tak, Paul P., Miceli-Richard, Corinne, Bang, So-Young, Lee, Hye-Soon, Martin, Javier, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Rantapää-Dahlqvist, Solbritt, Ärlestig, Lisbeth, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Eyre, Steve, Bowes, John, Barton, Anne, de Vries, Niek, Moreland, Larry W., Criswell, Lindsey A., Karlson, Elizabeth W., Taniguchi, Atsuo, Yamada, Ryo, Kubo, Michiaki, Liu, Jun S., Bae, Sang-Cheol, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Raychaudhuri, Soumya, Stranger, Barbara E., De Jager, Philip L., Franke, Lude, Visscher, Peter M., Brown, Matthew A., Yamanaka, Hisashi, Mimori, Tsuneyo, Takahashi, Atsushi, Xu, Huji, Behrens, Timothy W., Siminovitch, Katherine A., Momohara, Shigeki, Matsuda, Fumihiko, Yamamoto, Kazuhiko, Plenge, Robert M.
Publicado em 2013

Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes

Por Teumer, Alexander, Tin, Adrienne, Sorice, Rossella, Gorski, Mathias, Yeo, Nan Cher, Chu, Audrey Y., Li, Man, Li, Yong, Mijatovic, Vladan, Ko, Yi-An, Taliun, Daniel, Luciani, Alessandro, Chen, Ming-Huei, Yang, Qiong, Foster, Meredith C., Olden, Matthias, Hiraki, Linda T., Tayo, Bamidele O., Fuchsberger, Christian, Dieffenbach, Aida Karina, Shuldiner, Alan R., Smith, Albert V., Zappa, Allison M., Lupo, Antonio, Kollerits, Barbara, Ponte, Belen, Stengel, Bénédicte, Krämer, Bernhard K., Paulweber, Bernhard, Mitchell, Braxton D., Hayward, Caroline, Helmer, Catherine, Meisinger, Christa, Gieger, Christian, Shaffer, Christian M., Müller, Christian, Langenberg, Claudia, Ackermann, Daniel, Siscovick, David, Boerwinkle, Eric, Kronenberg, Florian, Ehret, Georg B., Homuth, Georg, Waeber, Gerard, Navis, Gerjan, Gambaro, Giovanni, Malerba, Giovanni, Eiriksdottir, Gudny, Li, Guo, Wichmann, H. Erich, Grallert, Harald, Wallaschofski, Henri, Völzke, Henry, Brenner, Herrmann, Kramer, Holly, Leach, I. Mateo, Rudan, Igor, Hillege, Hans L., Beckmann, Jacques S., Lambert, Jean Charles, Luan, Jian'an, Zhao, Jing Hua, Chalmers, John, Coresh, Josef, Denny, Joshua C., Butterbach, Katja, Launer, Lenore J., Ferrucci, Luigi, Kedenko, Lyudmyla, Haun, Margot, Metzger, Marie, Woodward, Mark, Hoffman, Matthew J., Nauck, Matthias, Waldenberger, Melanie, Pruijm, Menno, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Wareham, Nicholas J., Endlich, Nicole, Soranzo, Nicole, Polasek, Ozren, van der Harst, Pim, Pramstaller, Peter Paul, Vollenweider, Peter, Wild, Philipp S., Gansevoort, Ron T., Rettig, Rainer, Biffar, Reiner, Carroll, Robert J., Katz, Ronit, Loos, Ruth J.F., Hwang, Shih-Jen, Coassin, Stefan, Bergmann, Sven, Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Corre, Tanguy, Zeller, Tanja, Illig, Thomas, Aspelund, Thor, Tanaka, Toshiko, Lendeckel, Uwe, Völker, Uwe, Gudnason, Vilmundur, Chouraki, Vincent, Koenig, Wolfgang, Kutalik, Zoltan, O'Connell, Jeffrey R., Parsa, Afshin, Heid, Iris M., Paterson, Andrew D., de Boer, Ian H., Devuyst, Olivier, Lazar, Jozef, Endlich, Karlhans, Susztak, Katalin, Tremblay, Johanne, Hamet, Pavel, Jacob, Howard J., Böger, Carsten A., Fox, Caroline S., Pattaro, Cristian, Köttgen, Anna
Publicado no Diabetes (2016)

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

Por Li, Man, Li, Yong, Weeks, Olivia, Mijatovic, Vladan, Teumer, Alexander, Huffman, Jennifer E., Tromp, Gerard, Fuchsberger, Christian, Gorski, Mathias, Lyytikäinen, Leo-Pekka, Nutile, Teresa, Sedaghat, Sanaz, Sorice, Rossella, Tin, Adrienne, Yang, Qiong, Ahluwalia, Tarunveer S., Arking, Dan E., Bihlmeyer, Nathan A., Böger, Carsten A., Carroll, Robert J., Chasman, Daniel I., Cornelis, Marilyn C., Dehghan, Abbas, Faul, Jessica D., Feitosa, Mary F., Gambaro, Giovanni, Gasparini, Paolo, Giulianini, Franco, Heid, Iris, Huang, Jinyan, Imboden, Medea, Jackson, Anne U., Jeff, Janina, Jhun, Min A., Katz, Ronit, Kifley, Annette, Kilpeläinen, Tuomas O., Kumar, Ashish, Laakso, Markku, Li-Gao, Ruifang, Lohman, Kurt, Lu, Yingchang, Mägi, Reedik, Malerba, Giovanni, Mihailov, Evelin, Mohlke, Karen L., Mook-Kanamori, Dennis O., Robino, Antonietta, Ruderfer, Douglas, Salvi, Erika, Schick, Ursula M., Schulz, Christina-Alexandra, Smith, Albert V., Smith, Jennifer A., Traglia, Michela, Yerges-Armstrong, Laura M., Zhao, Wei, Goodarzi, Mark O., Kraja, Aldi T., Liu, Chunyu, Wessel, Jennifer, Boerwinkle, Eric, Borecki, Ingrid B., Bork-Jensen, Jette, Bottinger, Erwin P., Braga, Daniele, Brandslund, Ivan, Brody, Jennifer A., Campbell, Archie, Carey, David J., Christensen, Cramer, Coresh, Josef, Crook, Errol, Curhan, Gary C., Cusi, Daniele, de Boer, Ian H., de Vries, Aiko P.J., Denny, Joshua C., Devuyst, Olivier, Dreisbach, Albert W., Endlich, Karlhans, Esko, Tõnu, Franco, Oscar H., Fulop, Tibor, Gerhard, Glenn S., Glümer, Charlotte, Gottesman, Omri, Grarup, Niels, Gudnason, Vilmundur, Hansen, Torben, Harris, Tamara B., Hayward, Caroline, Hocking, Lynne, Hofman, Albert, Hu, Frank B., Husemoen, Lise Lotte N., Jackson, Rebecca D., Jørgensen, Torben, Jørgensen, Marit E., Kähönen, Mika, Kardia, Sharon L.R., König, Wolfgang, Kooperberg, Charles, Kriebel, Jennifer, Launer, Lenore J., Lauritzen, Torsten, Lehtimäki, Terho, Levy, Daniel, Linksted, Pamela, Linneberg, Allan, Liu, Yongmei, Loos, Ruth J.F., Lupo, Antonio, Meisinger, Christine, Melander, Olle, Metspalu, Andres, Mitchell, Paul, Nauck, Matthias, Nürnberg, Peter, Orho-Melander, Marju, Parsa, Afshin, Pedersen, Oluf, Peters, Annette, Peters, Ulrike, Polasek, Ozren, Porteous, David, Probst-Hensch, Nicole M., Psaty, Bruce M., Qi, Lu, Raitakari, Olli T., Reiner, Alex P., Rettig, Rainer, Ridker, Paul M., Rivadeneira, Fernando, Rossouw, Jacques E., Schmidt, Frank, Siscovick, David, Soranzo, Nicole, Strauch, Konstantin, Toniolo, Daniela, Turner, Stephen T., Uitterlinden, André G., Ulivi, Sheila, Velayutham, Dinesh, Völker, Uwe, Völzke, Henry, Waldenberger, Melanie, Wang, Jie Jin, Weir, David R., Witte, Daniel, Kuivaniemi, Helena, Fox, Caroline S., Franceschini, Nora, Goessling, Wolfram, Köttgen, Anna, Chu, Audrey Y.
Publicado no J Am Soc Nephrol (2017)

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Por Pattaro, Cristian, Teumer, Alexander, Gorski, Mathias, Chu, Audrey Y., Li, Man, Mijatovic, Vladan, Garnaas, Maija, Tin, Adrienne, Sorice, Rossella, Li, Yong, Taliun, Daniel, Olden, Matthias, Foster, Meredith, Yang, Qiong, Chen, Ming-Huei, Pers, Tune H., Johnson, Andrew D., Ko, Yi-An, Fuchsberger, Christian, Tayo, Bamidele, Nalls, Michael, Feitosa, Mary F., Isaacs, Aaron, Dehghan, Abbas, d'Adamo, Pio, Adeyemo, Adebowale, Dieffenbach, Aida Karina, Zonderman, Alan B., Nolte, Ilja M., van der Most, Peter J., Wright, Alan F., Shuldiner, Alan R., Morrison, Alanna C., Hofman, Albert, Smith, Albert V., Dreisbach, Albert W., Franke, Andre, Uitterlinden, Andre G., Metspalu, Andres, Tonjes, Anke, Lupo, Antonio, Robino, Antonietta, Johansson, Åsa, Demirkan, Ayse, Kollerits, Barbara, Freedman, Barry I., Ponte, Belen, Oostra, Ben A., Paulweber, Bernhard, Krämer, Bernhard K., Mitchell, Braxton D., Buckley, Brendan M., Peralta, Carmen A., Hayward, Caroline, Helmer, Catherine, Rotimi, Charles N., Shaffer, Christian M., Müller, Christian, Sala, Cinzia, van Duijn, Cornelia M., Saint-Pierre, Aude, Ackermann, Daniel, Shriner, Daniel, Ruggiero, Daniela, Toniolo, Daniela, Lu, Yingchang, Cusi, Daniele, Czamara, Darina, Ellinghaus, David, Siscovick, David S., Ruderfer, Douglas, Gieger, Christian, Grallert, Harald, Rochtchina, Elena, Atkinson, Elizabeth J., Holliday, Elizabeth G., Boerwinkle, Eric, Salvi, Erika, Bottinger, Erwin P., Murgia, Federico, Rivadeneira, Fernando, Ernst, Florian, Kronenberg, Florian, Hu, Frank B., Navis, Gerjan J., Curhan, Gary C., Ehret, George B., Homuth, Georg, Coassin, Stefan, Thun, Gian-Andri, Pistis, Giorgio, Gambaro, Giovanni, Malerba, Giovanni, Montgomery, Grant W., Eiriksdottir, Gudny, Jacobs, Gunnar, Li, Guo, Wichmann, H-Erich, Campbell, Harry, Schmidt, Helena, Wallaschofski, Henri, Völzke, Henry, Brenner, Hermann, Kroemer, Heyo K., Kramer, Holly, Lin, Honghuang, Leach, I. Mateo, Ford, Ian, Guessous, Idris, Rudan, Igor, Prokopenko, Inga, Borecki, Ingrid, Heid, Iris M., Kolcic, Ivana, Persico, Ivana, Jukema, J. Wouter, Wilson, James F., Felix, Janine F., Divers, Jasmin, Lambert, Jean-Charles, Stafford, Jeanette M., Gaspoz, Jean-Michel, Smith, Jennifer A., Faul, Jessica D., Wang, Jie Jin, Ding, Jingzhong, Hirschhorn, Joel N., Attia, John, Whitfield, John B., Chalmers, John, Viikari, Jorma, Coresh, Josef, Denny, Joshua C., Karjalainen, Juha, Fernandes, Jyotika K., Endlich, Karlhans, Butterbach, Katja, Keene, Keith L., Lohman, Kurt, Portas, Laura, Launer, Lenore J., Lyytikäinen, Leo-Pekka, Yengo, Loic, Franke, Lude, Ferrucci, Luigi, Rose, Lynda M., Kedenko, Lyudmyla, Rao, Madhumathi, Struchalin, Maksim, Kleber, Marcus E., Cavalieri, Margherita, Haun, Margot, Cornelis, Marilyn C., Ciullo, Marina, Pirastu, Mario, de Andrade, Mariza, McEvoy, Mark A., Woodward, Mark, Adam, Martin, Cocca, Massimiliano, Nauck, Matthias, Imboden, Medea, Waldenberger, Melanie, Pruijm, Menno, Metzger, Marie, Stumvoll, Michael, Evans, Michele K., Sale, Michele M., Kähönen, Mika, Boban, Mladen, Bochud, Murielle, Rheinberger, Myriam, Verweij, Niek, Bouatia-Naji, Nabila, Martin, Nicholas G., Hastie, Nick, Probst-Hensch, Nicole, Soranzo, Nicole, Devuyst, Olivier, Raitakari, Olli, Gottesman, Omri, Franco, Oscar H., Polasek, Ozren, Gasparini, Paolo, Munroe, Patricia B., Ridker, Paul M., Mitchell, Paul, Muntner, Paul, Meisinger, Christa, Smit, Johannes H., Kovacs, Peter, Wild, Philipp S., Froguel, Philippe, Rettig, Rainer, Mägi, Reedik, Biffar, Reiner, Schmidt, Reinhold, Middelberg, Rita P. S., Carroll, Robert J., Penninx, Brenda W., Scott, Rodney J., Katz, Ronit, Sedaghat, Sanaz, Wild, Sarah H., Kardia, Sharon L. R., Ulivi, Sheila, Hwang, Shih-Jen, Enroth, Stefan, Kloiber, Stefan, Trompet, Stella, Stengel, Benedicte, Hancock, Stephen J., Turner, Stephen T., Rosas, Sylvia E., Stracke, Sylvia, Harris, Tamara B., Zeller, Tanja, Zemunik, Tatijana, Lehtimäki, Terho, Illig, Thomas, Aspelund, Thor, Nikopensius, Tiit, Esko, Tonu, Tanaka, Toshiko, Gyllensten, Ulf, Völker, Uwe, Emilsson, Valur, Vitart, Veronique, Aalto, Ville, Gudnason, Vilmundur, Chouraki, Vincent, Chen, Wei-Min, Igl, Wilmar, März, Winfried, Koenig, Wolfgang, Lieb, Wolfgang, Loos, Ruth J. F., Liu, Yongmei, Snieder, Harold, Pramstaller, Peter P., Parsa, Afshin, O'Connell, Jeffrey R., Susztak, Katalin, Hamet, Pavel, Tremblay, Johanne, de Boer, Ian H., Böger, Carsten A., Goessling, Wolfram, Chasman, Daniel I., Köttgen, Anna, Kao, W. H. Linda, Fox, Caroline S.
Publicado no Nat Commun (2016)