Targeted Chromatin Capture (T2C): a novel high resolution high throughput method to detect genomic interactions and regulatory elements

Por Kolovos, Petros, van de Werken, Harmen JG, Kepper, Nick, Zuin, Jessica, Brouwer, Rutger WW, Kockx, Christel EM, Wendt, Kerstin S, van IJcken, Wilfred FJ, Grosveld, Frank, Knoch, Tobias A
Publicado em 2014

Deciphering the RNA landscape by RNAome sequencing

Por Derks, Kasper WJ, Misovic, Branislav, van den Hout, Mirjam CGN, Kockx, Christel EM, Payan Gomez, Cesar, Brouwer, Rutger WW, Vrieling, Harry, Hoeijmakers, Jan HJ, van IJcken, Wilfred FJ, Pothof, Joris
Publicado no RNA Biol (2015)

Comparison of Mycoplasma pneumoniae Genome Sequences from Strains Isolated from Symptomatic and Asymptomatic Patients

Por Spuesens, Emiel B. M., Brouwer, Rutger W. W., Mol, Kristin H. J. M., Hoogenboezem, Theo, Kockx, Christel E. M., Jansen, Ruud, Van IJcken, Wilfred F. J., Van Rossum, Annemarie M. C., Vink, Cornelis
Publicado no Front Microbiol (2016)

Genome-wide DNA methylation profiling of non-small cell lung carcinomas

Por Carvalho, Rejane Hughes, Haberle, Vanja, Hou, Jun, van Gent, Teus, Thongjuea, Supat, van IJcken, Wilfred, Kockx, Christel, Brouwer, Rutger, Rijkers, Erikjan, Sieuwerts, Anieta, Foekens, John, van Vroonhoven, Mirjam, Aerts, Joachim, Grosveld, Frank, Lenhard, Boris, Philipsen, Sjaak
Publicado em 2012

A Novel Complex, RUNX1-MYEF2, Represses Hematopoietic Genes in Erythroid Cells

Por van Riel, Boet, Pakozdi, Tibor, Brouwer, Rutger, Monteiro, Rui, Tuladhar, Kapil, Franke, Vedran, Bryne, Jan Christian, Jorna, Ruud, Rijkers, Erik-Jan, van Ijcken, Wilfred, Andrieu-Soler, Charlotte, Demmers, Jeroen, Patient, Roger, Soler, Eric, Lenhard, Boris, Grosveld, Frank
Publicado em 2012

The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes

Por Knoch, Tobias A., Wachsmuth, Malte, Kepper, Nick, Lesnussa, Michael, Abuseiris, Anis, Ali Imam, A. M., Kolovos, Petros, Zuin, Jessica, Kockx, Christel E. M., Brouwer, Rutger W. W., van de Werken, Harmen J. G., van IJcken, Wilfred F. J., Wendt, Kerstin S., Grosveld, Frank G.
Publicado no Epigenetics Chromatin (2016)

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

Por Zuin, Jessica, Dixon, Jesse R., van der Reijden, Michael I. J. A., Ye, Zhen, Kolovos, Petros, Brouwer, Rutger W. W., van de Corput, Mariëtte P. C., van de Werken, Harmen J. G., Knoch, Tobias A., van IJcken, Wilfred F. J., Grosveld, Frank G., Ren, Bing, Wendt, Kerstin S.
Publicado em 2014

The dystrophin gene and cognitive function in the general population

Por Vojinovic, Dina, Adams, Hieab HH, van der Lee, Sven J, Ibrahim-Verbaas, Carla A, Brouwer, Rutger, van den Hout, Mirjam CGN, Oole, Edwin, van Rooij, Jeroen, Uitterlinden, Andre, Hofman, Albert, van IJcken, Wilfred FJ, Aartsma-Rus, Annemieke, van Ommen, GertJan B, Ikram, M Arfan, van Duijn, Cornelia M, Amin, Najaf
Publicado no Eur J Hum Genet (2015)

Targeted Next Generation Sequencing reveals previously unidentified TSC1 and TSC2 mutations

Por Nellist, Mark, Brouwer, Rutger WW, Kockx, Christel EM, van Veghel-Plandsoen, Monique, Withagen-Hermans, Caroline, Prins-Bakker, Lida, Hoogeveen-Westerveld, Marianne, Mrsic, Alan, van den Berg, Mike MP, Koopmans, Anna E, de Wit, Marie-Claire, Jansen, Floor E, Maat-Kievit, Anneke JA, van den Ouweland, Ans, Halley, Dicky, de Klein, Annelies, van IJcken, Wilfred FJ
Publicado no BMC Med Genet (2015)

Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice

Por Halim, Danny, Wilson, Michael P., Oliver, Daniel, Brosens, Erwin, Verheij, Joke B. G. M., Han, Yu, Nanda, Vivek, Lyu, Qing, Doukas, Michael, Stoop, Hans, Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Slivano, Orazio J., Burns, Alan J., Christie, Christine K., de Mesy Bentley, Karen L., Brooks, Alice S., Tibboel, Dick, Xu, Suowen, Jin, Zheng Gen, Djuwantono, Tono, Yan, Wei, Alves, Maria M., Hofstra, Robert M. W., Miano, Joseph M.
Publicado no Proc Natl Acad Sci U S A (2017)

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

Por Meuwissen, Marije E.C., Schot, Rachel, Buta, Sofija, Oudesluijs, Grétel, Tinschert, Sigrid, Speer, Scott D., Li, Zhi, van Unen, Leontine, Heijsman, Daphne, Goldmann, Tobias, Lequin, Maarten H., Kros, Johan M., Stam, Wendy, Hermann, Mark, Willemsen, Rob, Brouwer, Rutger W.W., Van IJcken, Wilfred F.J., Martin-Fernandez, Marta, de Coo, Irenaeus, Dudink, Jeroen, de Vries, Femke A.T., Bertoli Avella, Aida, Prinz, Marco, Crow, Yanick J., Verheijen, Frans W., Pellegrini, Sandra, Bogunovic, Dusan, Mancini, Grazia M.S.
Publicado no J Exp Med (2016)

PLD3-variants in population studies

Por van der Lee, Sven J., Holstege, Henne, Wong, Tsz Hang, Jakobsdottir, Johanna, Bis, Joshua C., Chouraki, Vincent, van Rooij, Jeroen G.J., Grove, Megan L., Smith, Albert V., Amin, Najaf, Choi, Seung-Hoan, Beiser, Alexa S., Garcia, Melissa E., van IJcken, Wilfred F.J., Pijnenburg, Yolande A.L., Louwersheimer, Eva, Brouwer, Rutger W.W., van den Hout, Mirjam C.G.N., Oole, Edwin, Eirkisdottir, Gudny, Levy, Daniel, Rotter, Jerome I., Emilsson, Valur, O’Donnell, Christopher J., Aspelund, Thor, Uitterlinden, Andre G., Launer, Lenore J., Hofman, Albert, Boerwinkle, Eric, Psaty, Bruce M., DeStefano, Anita L., Scheltens, Philip, Seshadri, Sudha, van Swieten, John C., Gudnason, Vilmundur, van der Flier, Wiesje M., Ikram, M. Arfan, van Duijn, Cornelia M.
Publicado no Nature (2015)

Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes

Por Gui, Hongsheng, Schriemer, Duco, Cheng, William W., Chauhan, Rajendra K., Antiňolo, Guillermo, Berrios, Courtney, Bleda, Marta, Brooks, Alice S., Brouwer, Rutger W. W., Burns, Alan J., Cherny, Stacey S., Dopazo, Joaquin, Eggen, Bart J. L., Griseri, Paola, Jalloh, Binta, Le, Thuy-Linh, Lui, Vincent C. H., Luzón-Toro, Berta, Matera, Ivana, Ngan, Elly S. W., Pelet, Anna, Ruiz-Ferrer, Macarena, Sham, Pak C., Shepherd, Iain T., So, Man-Ting, Sribudiani, Yunia, Tang, Clara S. M., van den Hout, Mirjam C. G. N., van der Linde, Herma C., van Ham, Tjakko J., van IJcken, Wilfred F. J., Verheij, Joke B. G. M., Amiel, Jeanne, Borrego, Salud, Ceccherini, Isabella, Chakravarti, Aravinda, Lyonnet, Stanislas, Tam, Paul K. H., Garcia-Barceló, Maria-Mercè, Hofstra, Robert M. W.
Publicado no Genome Biol (2017)

Genetic variants in RBFOX3 are associated with sleep latency

Por Amin, Najaf, Allebrandt, Karla V, van der Spek, Ashley, Müller-Myhsok, Bertram, Hek, Karin, Teder-Laving, Maris, Hayward, Caroline, Esko, Tõnu, van Mill, Josine G, Mbarek, Hamdi, Watson, Nathaniel F, Melville, Scott A, Del Greco, Fabiola M, Byrne, Enda M, Oole, Edwin, Kolcic, Ivana, Chen, Ting-hsu, Evans, Daniel S, Coresh, Josef, Vogelzangs, Nicole, Karjalainen, Juha, Willemsen, Gonneke, Gharib, Sina A, Zgaga, Lina, Mihailov, Evelin, Stone, Katie L, Campbell, Harry, Brouwer, Rutger WW, Demirkan, Ayse, Isaacs, Aaron, Dogas, Zoran, Marciante, Kristin D, Campbell, Susan, Borovecki, Fran, Luik, Annemarie I, Li, Man, Hottenga, Jouke Jan, Huffman, Jennifer E, van den Hout, Mirjam CGN, Cummings, Steven R, Aulchenko, Yurii S, Gehrman, Philip R, Uitterlinden, André G, Wichmann, Heinz-Erich, Müller-Nurasyid, Martina, Fehrmann, Rudolf SN, Montgomery, Grant W, Hofman, Albert, Kao, Wen Hong Linda, Oostra, Ben A, Wright, Alan F, Vink, Jacqueline M, Wilson, James F, Pramstaller, Peter P, Hicks, Andrew A, Polasek, Ozren, Punjabi, Naresh M, Redline, Susan, Psaty, Bruce M, Heath, Andrew C, Merrow, Martha, Tranah, Gregory J, Gottlieb, Daniel J, Boomsma, Dorret I, Martin, Nicholas G, Rudan, Igor, Tiemeier, Henning, van IJcken, Wilfred FJ, Penninx, Brenda W, Metspalu, Andres, Meitinger, Thomas, Franke, Lude, Roenneberg, Till, van Duijn, Cornelia M
Publicado no Eur J Hum Genet (2016)