Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.

Por Klessig, D F, Brough, D E, Cleghon, V
Publicado em 1984

Restricted changes in the adenovirus DNA-binding protein that lead to extended host range or temperature-sensitive phenotypes.

Por Brough, D E, Rice, S A, Sell, S, Klessig, D F
Publicado em 1985

A gene transfer vector-cell line system for complete functional complementation of adenovirus early regions E1 and E4.

Por Brough, D E, Lizonova, A, Hsu, C, Kulesa, V A, Kovesdi, I
Publicado em 1996

An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation.

Por Brough, D E, Hofmann, T J, Ellwood, K B, Townley, R A, Cole, M D
Publicado em 1995

Adenovirus type 5 early region 4 is responsible for E1A-induced p53-independent apoptosis.

Por Marcellus, R C, Teodoro, J G, Wu, T, Brough, D E, Ketner, G, Shore, G C, Branton, P E
Publicado em 1996

Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo.

Por Brough, D E, Hsu, C, Kulesa, V A, Lee, G M, Cantolupo, L J, Lizonova, A, Kovesdi, I
Publicado em 1997

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

Por Wickham, T J, Tzeng, E, Shears, L L, Roelvink, P W, Li, Y, Lee, G M, Brough, D E, Lizonova, A, Kovesdi, I
Publicado em 1997