Chemical Lead Optimization of a pan G(q) mAChR M(1), M(3), M(5) Positive Allosteric Modulator (PAM) Lead. Part II. Development of potent and highly selective M(1) PAM

Autor Bridges, Thomas M., Kennedy, J. Phillip, Noetzel, Meredith J., Breininger, Micah L., Gentry, Patrick R., Conn, P. Jeffrey, Lindsley, Craig W.
Vydáno 2010

Chemical Lead Optimization of a pan G(q) mAChR M(1), M(3), M(5) Positive Allosteric Modulator (PAM) Lead. Part I. Development of the first highly selective M(5) PAM

Autor Bridges, Thomas M., Kennedy, J. Phillip, Cho, Hyekyung P., Breininger, Micah L., Gentry, Patrick R., Hopkins, Corey R., Conn, P. Jeffrey, Lindsley, Craig W.
Vydáno 2009

Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I. Exploration of alternative benzyl and privileged structure moieties

Autor Bridges, Thomas M., Brady, Ashley E., Kennedy, J. Phillip, Daniels, R. Nathan, Miller, Nicole R., Kim, Kwango, Breininger, Micah L., Gentry, Patrick R., Brogan, John T., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Vydáno 2008

Centrally Active Allosteric Potentiators of the M(4) Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

Autor Brady, Ashley E., Jones, Carrie K., Bridges, Thomas M., Kennedy, J. Phillip, Thompson, Analisa D., Heiman, Justin U., Breininger, Micah L., Gentry, Patrick R., Yin, Huiyong, Jadhav, Satyawan B., Shirey, Jana K., Conn, P. Jeffrey, Lindsley, Craig W.
Vydáno 2008