Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer’s disease

著者: Hager, Klaus, Baseman, Alan S, Nye, Jeffrey S, Brashear, H Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M
出版事項 2014

Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer’s disease: post-hoc analysis of a randomized placebo-contro...

著者: Hager, Klaus, Baseman, Alan S., Nye, Jeffrey S., Brashear, H. Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M.
出版年 Alzheimers Res Ther (2016)

First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheim...

著者: Delnomdedieu, Marielle, Duvvuri, Sridhar, Li, David Jianjun, Atassi, Nazem, Lu, Ming, Brashear, H. Robert, Liu, Enchi, Ness, Seth, Kupiec, James W.
出版年 Alzheimers Res Ther (2016)

Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis

著者: Arrighi, H Michael, Barakos, Jerome, Barkhof, Frederik, Tampieri, Donatella, Jack, Clifford, Melançon, Denis, Morris, Kristen, Ketter, Nzeera, Liu, Enchi, Brashear, H Robert
出版年 J Neurol Neurosurg Psychiatry (2016)

The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized con...

著者: Prins, Niels D, van der Flier, Wiesje A, Knol, Dirk L, Fox, Nick C, Brashear, H Robert, Nye, Jeffrey S, Barkhof, Frederik, Scheltens, Philip
出版年 Alzheimers Res Ther (2014)

Suicidal ideation and behavior assessment in dementia studies: An Internet survey

著者: Chappell, Phillip, Dubrava, Sarah, Stewart, Michelle, Hartley, Dean M., Alphs, Larry, Brashear, H. Robert, Conwell, Yeates, Miller, David, Schindler, Rachel J., Siemers, Eric R., Yaffe, Kristine
出版年 Alzheimers Dement (N Y) (2016)

Alzheimer's disease assessment scale-cognitive 11-item progression model in mild-to-moderate Alzheimer's disease trials of bapineuzumab

著者: Samtani, Mahesh N., Xu, Steven X., Russu, Alberto, Adedokun, Omoniyi J., Lu, Ming, Ito, Kaori, Corrigan, Brian, Raje, Sangeeta, Brashear, H. Robert, Styren, Scot, Hu, Chuanpu
出版年 Alzheimers Dement (N Y) (2015)

Alzheimer's disease progression model using disability assessment for dementia scores from bapineuzumab trials

著者: Xu, Steven X., Samtani, Mahesh N., Russu, Alberto, Adedokun, Omoniyi J., Lu, Ming, Ito, Kaori, Corrigan, Brian, Raje, Sangeeta, Brashear, H. Robert, Styren, Scot, Hu, Chuanpu
出版年 Alzheimers Dement (N Y) (2015)

Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-contro...

著者: Novak, Gerald, Streffer, Johannes Rolf, Timmers, Maarten, Henley, David, Brashear, H. Robert, Bogert, Jennifer, Russu, Alberto, Janssens, Luc, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan
出版年 Alzheimers Res Ther (2020)

Long-term safety and tolerability of bapineuzumab in patients with Alzheimer’s disease in two phase 3 extension studies

著者: Ivanoiu, Adrian, Pariente, Jérémie, Booth, Kevin, Lobello, Kasia, Luscan, Gerald, Hua, Lisa, Lucas, Prisca, Styren, Scot, Yang, Lingfeng, Li, David, Black, Ronald S., Brashear, H. Robert, McRae, Thomas
出版年 Alzheimers Res Ther (2016)

The pathway to secondary prevention of Alzheimer's disease

著者: McDade, Eric, Bednar, Martin M., Brashear, H. Robert, Miller, David S., Maruff, Paul, Randolph, Christopher, Ismail, Zahinoor, Carrillo, Maria C., Weber, Christopher J., Bain, Lisa J., Hake, Ann Marie
出版年 Alzheimers Dement (N Y) (2020)

Considerations for the assessment of suicidal ideation and behavior in older adults with cognitive decline and dementia

著者: Alphs, Larry, Brashear, H. Robert, Chappell, Phillip, Conwell, Yeates, Dubrava, Sarah, Khin, Ni A., Kozauer, Nicholas, Hartley, Dean M., Miller, David S., Schindler, Rachel J., Siemers, Eric R., Stewart, Michelle, Yaffe, Kristine
出版年 Alzheimers Dement (N Y) (2016)

Amyloid Related Imaging Abnormalities (ARIA) in Amyloid Modifying Therapeutic Trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

著者: Sperling, Reisa A., Jack, Clifford R., Black, Sandra E., Frosch, Matthew P., Greenberg, Steven M., Hyman, Bradley T., Scheltens, Philip, Carrillo, Maria C., Thies, William, Bednar, Martin M., Black, Ronald S., Brashear, H. Robert, Grundman, Michael, Siemers, Eric R., Feldman, Howard H., Schindler, Rachel J.
出版事項 2011

Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial

著者: Sperling, Reisa, Henley, David, Aisen, Paul S., Raman, Rema, Donohue, Michael C., Ernstrom, Karin, Rafii, Michael S., Streffer, Johannes, Shi, Yingqi, Karcher, Keith, Raghavan, Nandini, Tymofyeyev, Yevgen, Bogert, Jennifer, Brashear, H. Robert, Novak, Gerald, Thipphawong, John, Saad, Ziad S., Kolb, Hartmuth, Rofael, Hany, Sanga, Panna, Romano, Gary
出版年 JAMA Neurol (2021)

Bapineuzumab for mild to moderate Alzheimer’s disease in two global, randomized, phase 3 trials

著者: Vandenberghe, Rik, Rinne, Juha O., Boada, Mercè, Katayama, Sadao, Scheltens, Philip, Vellas, Bruno, Tuchman, Michael, Gass, Achim, Fiebach, Jochen B., Hill, Derek, Lobello, Kasia, Li, David, McRae, Tom, Lucas, Prisca, Evans, Iona, Booth, Kevin, Luscan, Gerald, Wyman, Bradley T., Hua, Lisa, Yang, Lingfeng, Brashear, H. Robert, Black, Ronald S.
出版年 Alzheimers Res Ther (2016)

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer’s Disease

著者: Salloway, Stephen, Sperling, Reisa, Fox, Nick C., Blennow, Kaj, Klunk, William, Raskind, Murray, Sabbagh, Marwan, Honig, Lawrence S., Porsteinsson, Anton P., Ferris, Steven, Reichert, Marcel, Ketter, Nzeera, Nejadnik, Bijan, Guenzler, Volkmar, Miloslavsky, Maja, Wang, Daniel, Lu, Yuan, Lull, Julia, Tudor, Iulia Cristina, Liu, Enchi, Grundman, Michael, Yuen, Eric, Black, Ronald, Brashear, H. Robert
出版事項 2014

Amyloid-β (11)C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

著者: Liu, Enchi, Schmidt, Mark E., Margolin, Richard, Sperling, Reisa, Koeppe, Robert, Mason, Neale S., Klunk, William E., Mathis, Chester A., Salloway, Stephen, Fox, Nick C., Hill, Derek L., Les, Andrea S., Collins, Peter, Gregg, Keith M., Di, Jianing, Lu, Yuan, Tudor, I. Cristina, Wyman, Bradley T., Booth, Kevin, Broome, Stephanie, Yuen, Eric, Grundman, Michael, Brashear, H. Robert
出版年 Neurology (2015)