Effects of galantamine in a 2-year, randomized, placebo-controlled study in Alzheimer’s disease

Por Hager, Klaus, Baseman, Alan S, Nye, Jeffrey S, Brashear, H Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M
Publicado em 2014

Effect of concomitant use of memantine on mortality and efficacy outcomes of galantamine-treated patients with Alzheimer’s disease: post-hoc analysis of a randomized placebo-contro...

Por Hager, Klaus, Baseman, Alan S., Nye, Jeffrey S., Brashear, H. Robert, Han, John, Sano, Mary, Davis, Bonnie, Richards, Henry M.
Publicado no Alzheimers Res Ther (2016)

First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheim...

Por Delnomdedieu, Marielle, Duvvuri, Sridhar, Li, David Jianjun, Atassi, Nazem, Lu, Ming, Brashear, H. Robert, Liu, Enchi, Ness, Seth, Kupiec, James W.
Publicado no Alzheimers Res Ther (2016)

Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: a historical, prospective secondary analysis

Por Arrighi, H Michael, Barakos, Jerome, Barkhof, Frederik, Tampieri, Donatella, Jack, Clifford, Melançon, Denis, Morris, Kristen, Ketter, Nzeera, Liu, Enchi, Brashear, H Robert
Publicado no J Neurol Neurosurg Psychiatry (2016)

The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized con...

Por Prins, Niels D, van der Flier, Wiesje A, Knol, Dirk L, Fox, Nick C, Brashear, H Robert, Nye, Jeffrey S, Barkhof, Frederik, Scheltens, Philip
Publicado no Alzheimers Res Ther (2014)

Suicidal ideation and behavior assessment in dementia studies: An Internet survey

Por Chappell, Phillip, Dubrava, Sarah, Stewart, Michelle, Hartley, Dean M., Alphs, Larry, Brashear, H. Robert, Conwell, Yeates, Miller, David, Schindler, Rachel J., Siemers, Eric R., Yaffe, Kristine
Publicado no Alzheimers Dement (N Y) (2016)

Alzheimer's disease assessment scale-cognitive 11-item progression model in mild-to-moderate Alzheimer's disease trials of bapineuzumab

Por Samtani, Mahesh N., Xu, Steven X., Russu, Alberto, Adedokun, Omoniyi J., Lu, Ming, Ito, Kaori, Corrigan, Brian, Raje, Sangeeta, Brashear, H. Robert, Styren, Scot, Hu, Chuanpu
Publicado no Alzheimers Dement (N Y) (2015)

Alzheimer's disease progression model using disability assessment for dementia scores from bapineuzumab trials

Por Xu, Steven X., Samtani, Mahesh N., Russu, Alberto, Adedokun, Omoniyi J., Lu, Ming, Ito, Kaori, Corrigan, Brian, Raje, Sangeeta, Brashear, H. Robert, Styren, Scot, Hu, Chuanpu
Publicado no Alzheimers Dement (N Y) (2015)

Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-contro...

Por Novak, Gerald, Streffer, Johannes Rolf, Timmers, Maarten, Henley, David, Brashear, H. Robert, Bogert, Jennifer, Russu, Alberto, Janssens, Luc, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan
Publicado no Alzheimers Res Ther (2020)

Long-term safety and tolerability of bapineuzumab in patients with Alzheimer’s disease in two phase 3 extension studies

Por Ivanoiu, Adrian, Pariente, Jérémie, Booth, Kevin, Lobello, Kasia, Luscan, Gerald, Hua, Lisa, Lucas, Prisca, Styren, Scot, Yang, Lingfeng, Li, David, Black, Ronald S., Brashear, H. Robert, McRae, Thomas
Publicado no Alzheimers Res Ther (2016)

The pathway to secondary prevention of Alzheimer's disease

Por McDade, Eric, Bednar, Martin M., Brashear, H. Robert, Miller, David S., Maruff, Paul, Randolph, Christopher, Ismail, Zahinoor, Carrillo, Maria C., Weber, Christopher J., Bain, Lisa J., Hake, Ann Marie
Publicado no Alzheimers Dement (N Y) (2020)

Considerations for the assessment of suicidal ideation and behavior in older adults with cognitive decline and dementia

Por Alphs, Larry, Brashear, H. Robert, Chappell, Phillip, Conwell, Yeates, Dubrava, Sarah, Khin, Ni A., Kozauer, Nicholas, Hartley, Dean M., Miller, David S., Schindler, Rachel J., Siemers, Eric R., Stewart, Michelle, Yaffe, Kristine
Publicado no Alzheimers Dement (N Y) (2016)

Amyloid Related Imaging Abnormalities (ARIA) in Amyloid Modifying Therapeutic Trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

Por Sperling, Reisa A., Jack, Clifford R., Black, Sandra E., Frosch, Matthew P., Greenberg, Steven M., Hyman, Bradley T., Scheltens, Philip, Carrillo, Maria C., Thies, William, Bednar, Martin M., Black, Ronald S., Brashear, H. Robert, Grundman, Michael, Siemers, Eric R., Feldman, Howard H., Schindler, Rachel J.
Publicado em 2011

Findings of Efficacy, Safety, and Biomarker Outcomes of Atabecestat in Preclinical Alzheimer Disease: A Truncated Randomized Phase 2b/3 Clinical Trial

Por Sperling, Reisa, Henley, David, Aisen, Paul S., Raman, Rema, Donohue, Michael C., Ernstrom, Karin, Rafii, Michael S., Streffer, Johannes, Shi, Yingqi, Karcher, Keith, Raghavan, Nandini, Tymofyeyev, Yevgen, Bogert, Jennifer, Brashear, H. Robert, Novak, Gerald, Thipphawong, John, Saad, Ziad S., Kolb, Hartmuth, Rofael, Hany, Sanga, Panna, Romano, Gary
Publicado no JAMA Neurol (2021)

Bapineuzumab for mild to moderate Alzheimer’s disease in two global, randomized, phase 3 trials

Por Vandenberghe, Rik, Rinne, Juha O., Boada, Mercè, Katayama, Sadao, Scheltens, Philip, Vellas, Bruno, Tuchman, Michael, Gass, Achim, Fiebach, Jochen B., Hill, Derek, Lobello, Kasia, Li, David, McRae, Tom, Lucas, Prisca, Evans, Iona, Booth, Kevin, Luscan, Gerald, Wyman, Bradley T., Hua, Lisa, Yang, Lingfeng, Brashear, H. Robert, Black, Ronald S.
Publicado no Alzheimers Res Ther (2016)

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer’s Disease

Por Salloway, Stephen, Sperling, Reisa, Fox, Nick C., Blennow, Kaj, Klunk, William, Raskind, Murray, Sabbagh, Marwan, Honig, Lawrence S., Porsteinsson, Anton P., Ferris, Steven, Reichert, Marcel, Ketter, Nzeera, Nejadnik, Bijan, Guenzler, Volkmar, Miloslavsky, Maja, Wang, Daniel, Lu, Yuan, Lull, Julia, Tudor, Iulia Cristina, Liu, Enchi, Grundman, Michael, Yuen, Eric, Black, Ronald, Brashear, H. Robert
Publicado em 2014

Amyloid-β (11)C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

Por Liu, Enchi, Schmidt, Mark E., Margolin, Richard, Sperling, Reisa, Koeppe, Robert, Mason, Neale S., Klunk, William E., Mathis, Chester A., Salloway, Stephen, Fox, Nick C., Hill, Derek L., Les, Andrea S., Collins, Peter, Gregg, Keith M., Di, Jianing, Lu, Yuan, Tudor, I. Cristina, Wyman, Bradley T., Booth, Kevin, Broome, Stephanie, Yuen, Eric, Grundman, Michael, Brashear, H. Robert
Publicado no Neurology (2015)