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Amyloid-β (11)C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

OBJECTIVE: To evaluate the effects of bapineuzumab on brain β-amyloid (Aβ) burden using (11)C-Pittsburgh compound B ((11)C-PiB)-PET. METHODS: Two phase 3 clinical trials, 1 each in apolipoprotein APOE ε4 carriers and noncarriers, were conducted in patients with mild to moderate Alzheimer disease dem...

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Bibliografiska uppgifter
I publikationen:Neurology
Huvudupphovsmän: Liu, Enchi, Schmidt, Mark E., Margolin, Richard, Sperling, Reisa, Koeppe, Robert, Mason, Neale S., Klunk, William E., Mathis, Chester A., Salloway, Stephen, Fox, Nick C., Hill, Derek L., Les, Andrea S., Collins, Peter, Gregg, Keith M., Di, Jianing, Lu, Yuan, Tudor, I. Cristina, Wyman, Bradley T., Booth, Kevin, Broome, Stephanie, Yuen, Eric, Grundman, Michael, Brashear, H. Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Lippincott Williams & Wilkins 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553028/
https://ncbi.nlm.nih.gov/pubmed/26208959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001877
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