Up-regulation of Survivin during Immortalization of Human Myofibroblasts Is Linked to Repression of Tumor Suppressor p16(INK4a) Protein and Confers Resistance to Oxidative Stress

Por Kan, Chin-Yi, Petti, Carlotta, Bracken, Lauryn, Maritz, Michelle, Xu, Ning, O'Brien, Rosemary, Yang, Chen, Liu, Tao, Yuan, Jun, Lock, Richard B., MacKenzie, Karen L.
Publicado em 2013

AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia

Por Moradi Manesh, Donya, El-Hoss, Jad, Evans, Kathryn, Richmond, Jennifer, Toscan, Cara E., Bracken, Lauryn S., Hedrick, Ashlee, Sutton, Rosemary, Marshall, Glenn M., Wilson, William R., Kurmasheva, Raushan T., Billups, Catherine, Houghton, Peter J., Smith, Malcolm A., Carol, Hernan, Lock, Richard B.
Publicado no Blood (2015)

Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia

Por Suryani, Santi, Bracken, Lauryn S., Harvey, Richard C., Sia, Keith C.S., Carol, Hernan, Chen, I-Ming, Evans, Kathryn, Dietrich, Philipp A., Roberts, Kathryn G., Kurmasheva, Raushan T., Billups, Catherine A., Mullighan, Charles G., Willman, Cheryl L., Loh, Mignon L., Hunger, Stephen P., Houghton, Peter, Smith, Malcolm A., Lock, Richard B.
Publicado no Mol Cancer Ther (2014)

Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

Por Waibel, Michaela, Solomon, Vanessa S., Knight, Deborah A., Ralli, Rachael A., Kim, Sang-Kyu, Banks, Kellie-Marie, Vidacs, Eva, Virely, Clemence, Sia, Keith C.S., Bracken, Lauryn S., Collins-Underwood, Racquel, Drenberg, Christina, Ramsey, Laura B., Meyer, Sara C., Takiguchi, Megumi, Dickins, Ross A., Levine, Ross, Ghysdael, Jacques, Dawson, Mark A., Lock, Richard B., Mullighan, Charles G., Johnstone, Ricky W.
Publicado em 2013

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Por Goossens, Steven, Radaelli, Enrico, Blanchet, Odile, Durinck, Kaat, Van der Meulen, Joni, Peirs, Sofie, Taghon, Tom, Tremblay, Cedric S., Costa, Magdaline, Ghahremani, Morvarid Farhang, De Medts, Jelle, Bartunkova, Sonia, Haigh, Katharina, Schwab, Claire, Farla, Natalie, Pieters, Tim, Matthijssens, Filip, Van Roy, Nadine, Best, J. Adam, Deswarte, Kim, Bogaert, Pieter, Carmichael, Catherine, Rickard, Adam, Suryani, Santi, Bracken, Lauryn S., Alserihi, Raed, Canté-Barrett, Kirsten, Haenebalcke, Lieven, Clappier, Emmanuelle, Rondou, Pieter, Slowicka, Karolina, Huylebroeck, Danny, Goldrath, Ananda W., Janzen, Viktor, McCormack, Matthew P., Lock, Richard B., Curtis, David J., Harrison, Christine, Berx, Geert, Speleman, Frank, Meijerink, Jules P. P., Soulier, Jean, Van Vlierberghe, Pieter, Haigh, Jody J.
Publicado no Nat Commun (2015)