Key analogs of a uniquely potent synthetic vinblastine that contain modifications of the C20′ ethyl substituent

od Allemann, Oliver, Cross, R. Matthew, Brütsch, Manuela M., Radakovic, Aleksandar, Boger, Dale L.
izdano v Bioorg Med Chem Lett (2017)

Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer–dimer interface

od Carney, Daniel W., Lukesh, John C., Brody, Daniel M., Brütsch, Manuela M., Boger, Dale L.
izdano v Proc Natl Acad Sci U S A (2016)

Total synthesis of a key series of vinblastines modified at C4 that define the importance and surprising trends in activity

od Yang, Shouliang, Sankar, Kuppusamy, Skepper, Colin K., Barker, Timothy J., Lukesh III, John C., Brody, Daniel M., Brütsch, Manuela M., Boger, Dale L.
izdano v Chem Sci (2017)

Vinblastine 20’ Amides: Synthetic Analogs That Maintain or Improve Potency and Simultaneously Overcome Pgp-derived Efflux and Resistance

od Lukesh, John C., Carney, Daniel W., Dong, Huijun, Cross, R. Matthew, Shukla, Vyom, Duncan, Katharine K., Yang, Shouliang, Brody, Daniel M., Brütsch, Manuela M., Radakovic, Aleksandar, Boger, Dale L.
izdano v J Med Chem (2017)