Tandem Dienone-Photorearrangement-Cycloaddition for the Rapid Generation of Molecular Complexity

por Bos, Pieter H., Antalek, Mitchell T., Porco, John A., Stephenson, Corey R. J.
Publicado em 2013

K-Ras(G12D) has an allosteric small molecule binding site

por Feng, Huizhong, Zhang, Yan, Bos, Pieter H., Chambers, Jennifer M., Dupont, Marcel M., Stockwell, Brent R.
Publicado no Biochemistry (2019)

Development of MAP4 kinase inhibitors as motor-neuron-protecting agents

por Bos, Pieter H., Lowry, Emily R., Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R.
Publicado no Cell Chem Biol (2019)

Copper-binding small molecule induces oxidative stress and cell cycle arrest in glioblastoma-patient-derived cells

por Shimada, Kenichi, Reznik, Eduard, Stokes, Michael E., Krishnamoorthy, Lakshmi, Bos, Pieter H., Song, Yuyu, Quartararo, Christine E., Pagano, Nen C., Carpizo, Darren R., deCarvalho, Ana C., Lo, Donald C., Stockwell, Brent R.
Publicado no Cell Chem Biol (2018)

Multivalent small molecule pan-RAS inhibitors

por Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Publicado no Cell (2017)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation

por Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Lingplak, Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, Keith A., Stockwell, Brent R.
Publicado no Nat Chem Biol (2018)