Tandem Dienone-Photorearrangement-Cycloaddition for the Rapid Generation of Molecular Complexity

door Bos, Pieter H., Antalek, Mitchell T., Porco, John A., Stephenson, Corey R. J.
Gepubliceerd in 2013

K-Ras(G12D) has an allosteric small molecule binding site

door Feng, Huizhong, Zhang, Yan, Bos, Pieter H., Chambers, Jennifer M., Dupont, Marcel M., Stockwell, Brent R.
Gepubliceerd in Biochemistry (2019)

Development of MAP4 kinase inhibitors as motor-neuron-protecting agents

door Bos, Pieter H., Lowry, Emily R., Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R.
Gepubliceerd in Cell Chem Biol (2019)

Copper-binding small molecule induces oxidative stress and cell cycle arrest in glioblastoma-patient-derived cells

door Shimada, Kenichi, Reznik, Eduard, Stokes, Michael E., Krishnamoorthy, Lakshmi, Bos, Pieter H., Song, Yuyu, Quartararo, Christine E., Pagano, Nen C., Carpizo, Darren R., deCarvalho, Ana C., Lo, Donald C., Stockwell, Brent R.
Gepubliceerd in Cell Chem Biol (2018)

Multivalent small molecule pan-RAS inhibitors

door Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Gepubliceerd in Cell (2017)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation

door Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Lingplak, Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, Keith A., Stockwell, Brent R.
Gepubliceerd in Nat Chem Biol (2018)