Tandem Dienone-Photorearrangement-Cycloaddition for the Rapid Generation of Molecular Complexity

di Bos, Pieter H., Antalek, Mitchell T., Porco, John A., Stephenson, Corey R. J.
Pubblicazione 2013

K-Ras(G12D) has an allosteric small molecule binding site

di Feng, Huizhong, Zhang, Yan, Bos, Pieter H., Chambers, Jennifer M., Dupont, Marcel M., Stockwell, Brent R.
Pubblicato in Biochemistry (2019)

Development of MAP4 kinase inhibitors as motor-neuron-protecting agents

di Bos, Pieter H., Lowry, Emily R., Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R.
Pubblicato in Cell Chem Biol (2019)

Copper-binding small molecule induces oxidative stress and cell cycle arrest in glioblastoma-patient-derived cells

di Shimada, Kenichi, Reznik, Eduard, Stokes, Michael E., Krishnamoorthy, Lakshmi, Bos, Pieter H., Song, Yuyu, Quartararo, Christine E., Pagano, Nen C., Carpizo, Darren R., deCarvalho, Ana C., Lo, Donald C., Stockwell, Brent R.
Pubblicato in Cell Chem Biol (2018)

Multivalent small molecule pan-RAS inhibitors

di Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Pubblicato in Cell (2017)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation

di Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Lingplak, Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, Keith A., Stockwell, Brent R.
Pubblicato in Nat Chem Biol (2018)