Tandem Dienone-Photorearrangement-Cycloaddition for the Rapid Generation of Molecular Complexity

by Bos, Pieter H., Antalek, Mitchell T., Porco, John A., Stephenson, Corey R. J.
Published 2013

K-Ras(G12D) has an allosteric small molecule binding site

by Feng, Huizhong, Zhang, Yan, Bos, Pieter H., Chambers, Jennifer M., Dupont, Marcel M., Stockwell, Brent R.
Published in Biochemistry (2019)

Development of MAP4 kinase inhibitors as motor-neuron-protecting agents

by Bos, Pieter H., Lowry, Emily R., Costa, Jonathon, Thams, Sebastian, Garcia-Diaz, Alejandro, Zask, Arie, Wichterle, Hynek, Stockwell, Brent R.
Published in Cell Chem Biol (2019)

Copper-binding small molecule induces oxidative stress and cell cycle arrest in glioblastoma-patient-derived cells

by Shimada, Kenichi, Reznik, Eduard, Stokes, Michael E., Krishnamoorthy, Lakshmi, Bos, Pieter H., Song, Yuyu, Quartararo, Christine E., Pagano, Nen C., Carpizo, Darren R., deCarvalho, Ana C., Lo, Donald C., Stockwell, Brent R.
Published in Cell Chem Biol (2018)

Multivalent small molecule pan-RAS inhibitors

by Welsch, Matthew E., Kaplan, Anna, Chambers, Jennifer M., Stokes, Michael E., Bos, Pieter H., Zask, Arie, Zhang, Yan, Sanchez-Martin, Marta, Badgley, Michael A., Huang, Christine S., Tran, Timothy H., Akkiraju, Hemanth, Brown, Lewis M., Nandakumar, Renu, Cremers, Serge, Yang, Wan S., Tong, Liang, Olive, Kenneth P., Ferrando, Adolfo, Stockwell, Brent R.
Published in Cell (2017)

FINO(2) Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation

by Gaschler, Michael M., Andia, Alexander A., Liu, Hengrui, Csuka, Joleen M., Hurlocker, Brisa, Vaiana, Christopher A., Heindel, Daniel W., Zuckerman, Dylan S., Bos, Pieter H., Reznik, Eduard, Ye, Lingplak, Tyurina, Yulia Y., Lin, Annie J., Shchepinov, Mikhail S., Chan, Amy Y., Peguero-Pereira, Eveliz, Fomich, Maksim A., Daniels, Jacob. D., Bekish, Andrei V., Shmanai, Vadim V., Kagan, Valerian E., Mahal, Lara K., Woerpel, Keith A., Stockwell, Brent R.
Published in Nat Chem Biol (2018)