Evaluating the Dopamine Hypothesis of Schizophrenia in a Large-Scale Genome-Wide Association Study

Por Edwards, Alexis C., Bacanu, Silviu-Alin, Bigdeli, Tim B., Moscati, Arden, Kendler, Kenneth S.
Publicado no Schizophr Res (2016)

Association analysis of the PIP4K2A gene on chromosome 10p12 and schizophrenia in the Irish study of high density schizophrenia families (ISHDSF) and the Irish case-control study o...

Por Thiselton, D.L., Maher, B.S., Webb, B.T., Bigdeli, T.B., O’Neill, F.A., Walsh, D., Kendler, K.S., Riley, B.P.
Publicado em 2010

SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE

Por Docherty, A R, Moscati, A, Peterson, R, Edwards, A C, Adkins, D E, Bacanu, S A, Bigdeli, T B, Webb, B T, Flint, J, Kendler, K S
Publicado no Transl Psychiatry (2016)

Polygenic risk for severe psychopathology among Europeans is associated with major depressive disorder in Han Chinese women

Por Edwards, A. C., Docherty, A. R., Moscati, A., Bigdeli, T. B., Peterson, R. E., Webb, B. T., Bacanu, S.-A., Hettema, J. M., Flint, J., Kendler, K. S.
Publicado no Psychol Med (2017)

Molecular genetic analysis subdivided by adversity exposure suggests etiologic heterogeneity in major depression

Por Peterson, Roseann E., Cai, Na, Dahl, Andy W., Bigdeli, Tim B., Edwards, Alexis C., Webb, Bradley T., Bacanu, Silviu-Alin, Zaitlen, Noah, Flint, Jonathan, Kendler, Kenneth S.
Publicado no Am J Psychiatry (2018)

Chronicity of depression and molecular markers in a large sample of Han Chinese women

Por Edwards, Alexis C., Aggen, Steven H., Cai, Na, Bigdeli, Tim B., Peterson, Roseann E., Docherty, Anna R., Webb, Bradley T., Bacanu, Silviu-Alin, Flint, Jonathan, Kendler, Kenneth S.
Publicado no Depress Anxiety (2016)

The Genetic Architecture of Major Depressive Disorder in Han Chinese Women

Por Peterson, Roseann E., Cai, Na, Bigdeli, Tim B., Li, Yihan, Reimers, Mark, Nikulova, Anna, Webb, Bradley T., Bacanu, Silviu-Alin, Riley, Brien P., Flint, Jonathan, Kendler, Kenneth S.
Publicado no JAMA Psychiatry (2017)

11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project

Por Cai, Na, Bigdeli, Tim B., Kretzschmar, Warren W., Li, Yihan, Liang, Jieqin, Hu, Jingchu, Peterson, Roseann E., Bacanu, Silviu, Webb, Bradley Todd, Riley, Brien, Li, Qibin, Marchini, Jonathan, Mott, Richard, Kendler, Kenneth S., Flint, Jonathan
Publicado no Sci Data (2017)

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior

Por Salvatore, J E, Edwards, A C, McClintick, J N, Bigdeli, T B, Adkins, A, Aliev, F, Edenberg, H J, Foroud, T, Hesselbrock, V, Kramer, J, Nurnberger, J I, Schuckit, M, Tischfield, J A, Xuei, X, Dick, D M
Publicado no Transl Psychiatry (2015)

Meta-analysis of Positive and Negative Symptoms Reveals Schizophrenia Modifier Genes

Por Edwards, Alexis C., Bigdeli, Tim B., Docherty, Anna R., Bacanu, Silviu, Lee, Donghyung, de Candia, Teresa R., Moscati, Arden, Thiselton, Dawn L., Maher, Brion S., Wormley, Brandon K., Walsh, Dermot, O’Neill, Francis A., Kendler, Kenneth S., Riley, Brien P., Fanous, Ayman H.
Publicado no Schizophr Bull (2016)

Polygenic Risk Score Prediction of Alcohol Dependence Symptoms Across Population-Based and Clinically Ascertained Samples

Por Savage, Jeanne E., Salvatore, Jessica E., Aliev, Fazil, Edwards, Alexis C., Hickman, Matthew, Kendler, Kenneth S., Macleod, John, Latvala, Antti, Loukola, Anu, Kaprio, Jaakko, Rose, Richard J., Chan, Grace, Hesselbrock, Victor, Webb, Bradley T., Adkins, Amy, Bigdeli, Tim B., Riley, Brien P., Dick, Danielle M.
Publicado no Alcohol Clin Exp Res (2018)

Genome-Wide Association Study Reveals Greater Polygenic Loading for Schizophrenia in Cases With a Family History of Illness

Por Bigdeli, Tim B., Ripke, Stephan, Bacanu, Silviu-Alin, Lee, Sang Hong, Wray, Naomi R., Gejman, Pablo V., Rietschel, Marcella, Cichon, Sven, St Clair, David, Corvin, Aiden, Kirov, George, McQuillin, Andrew, Gurling, Hugh, Rujescu, Dan, Andreassen, Ole A., Werge, Thomas, Blackwood, Douglas H.R., Pato, Carlos N., Pato, Michele T., Malhotra, Anil K., O’Donovan, Michael C., Kendler, Kenneth S., Fanous, Ayman H.
Publicado no Am J Med Genet B Neuropsychiatr Genet (2015)

The AVPR1A Gene and Substance Use Disorders: Association, Replication, and Functional Evidence

Por Maher, Brion S., Vladimirov, Vladimir I., Latendresse, Shawn J., Thiselton, Dawn L., McNamee, Rebecca, Kang, Moonsu, Bigdeli, Tim B., Chen, Xiangning, Riley, Brien P., Hettema, John M., Chilcoat, Howard, Heidbreder, Christian, Muglia, Pierandrea, Murrelle, E. Lenn, Dick, Danielle M., Aliev, Fazil, Agrawal, Arpana, Edenberg, Howard J., Kramer, John, Nurnberger, John, Tischfield, Jay A., Devlin, Bernie, Ferrell, Robert E., Kirillova, Galina P., Tarter, Ralph E., Kendler, Kenneth S., Vanyukov, Michael M.
Publicado em 2011

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior

Por Tielbeek, Jorim J, Johansson, Ada, Polderman, Tinca JC, Rautiainen, Marja-Riitta, Jansen, Philip, Taylor, Michelle, Tong, Xiaoran, Lu, Qing, Burt, Alexandra S, Tiemeier, Henning, Viding, Essi, Plomin, Robert, Martin, Nicholas G, Heath, Andrew C, Madden, Pamela AF, Montgomery, Grant, Beaver, Kevin M, Waldman, Irwin, Gelernter, Joel, Kranzler, Henry R, Farrer, Lindsay A, Perry, John R B, Munafò, Marcus, LoParo, Devon, Paunio, Tiina, Tiihonen, Jari, Mous, Sabine E, Pappa, Irene, de Leeuw, Christiaan, Watanabe, Kyoko, Hammerschlag, Anke R, Salvatore, Jessica E., Aliev, Fazil, Bigdeli, Tim B., Dick, Danielle, Faraone, Stephen V, Popma, Arne, Medland, Sarah E, Posthuma, Danielle
Publicado no JAMA Psychiatry (2017)

Enhancing Psychosis-Spectrum Nosology Through an International Data Sharing Initiative

Por Docherty, Anna R, Fonseca-Pedrero, Eduardo, Debbané, Martin, Chan, Raymond C K, Linscott, Richard J, Jonas, Katherine G, Cicero, David C, Green, Melissa J, Simms, Leonard J, Mason, Oliver, Watson, David, Ettinger, Ulrich, Waszczuk, Monika, Rapp, Alexander, Grant, Phillip, Kotov, Roman, DeYoung, Colin G, Ruggero, Camilo J, Eaton, Nicolas R, Krueger, Robert F, Patrick, Christopher, Hopwood, Christopher, O’Neill, F Anthony, Zald, David H, Conway, Christopher C, Adkins, Daniel E, Waldman, Irwin D, van Os, Jim, Sullivan, Patrick F, Anderson, John S, Shabalin, Andrey A, Sponheim, Scott R, Taylor, Stephan F, Grazioplene, Rachel G, Bacanu, Silviu A, Bigdeli, Tim B, Haenschel, Corinna, Malaspina, Dolores, Gooding, Diane C, Nicodemus, Kristin, Schultze-Lutter, Frauke, Barrantes-Vidal, Neus, Mohr, Christine, Carpenter, William T, Cohen, Alex S
Publicado no Schizophr Bull (2018)

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-response Behaviors in Model Organisms

Por Adkins, Amy E., Hack, Laura M., Bigdeli, Tim B., Williamson, Vernell S., McMichael, G. Omari, Mamdani, Mohammed, Edwards, Alexis, Aliev, Fazil, Chan, Robin F., Bhandari, Poonam, Raabe, Richard C., Alaimo, Joseph T., Blackwell, GinaMari G., Moscati, Arden A., Poland, Ryan S., Rood, Benjamin, Patterson, Diana G., Walsh, Dermot, Whitfield, John B., Zhu, Gu, Montgomery, Grant W., Henders, Anjali K., Martin, Nicholas G., Heath, Andrew C., Madden, Pamela A.F., Frank, Josef, Ridinger, Monika, Wodarz, Norbert, Soyka, Michael, Zill, Peter, Ising, Marcus, Nöthen, Markus M, Kiefer, Falk, Rietschel, Marcella, Gelernter, Joel, Sherva, Richard, Koesterer, Ryan, Almasy, Laura, Zhao, Hongyu, Kranzler, Henry R., Farrer, Lindsay A., Maher, Brion S., Prescott, Carol A., Dick, Danielle M., Bacanu, Silviu A., Mathies, Laura D., Davies, Andrew G., Vladimirov, Vladimir I., Grotewiel, Mike, Bowers, M. Scott, Bettinger, Jill C., Webb, Bradley T., Miles, Michael F., Kendler, Kenneth S., Riley, Brien P.
Publicado no Alcohol Clin Exp Res (2017)

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

Por Stringer, S, Minică, C C, Verweij, K J H, Mbarek, H, Bernard, M, Derringer, J, van Eijk, K R, Isen, J D, Loukola, A, Maciejewski, D F, Mihailov, E, van der Most, P J, Sánchez-Mora, C, Roos, L, Sherva, R, Walters, R, Ware, J J, Abdellaoui, A, Bigdeli, T B, Branje, S J T, Brown, S A, Bruinenberg, M, Casas, M, Esko, T, Garcia-Martinez, I, Gordon, S D, Harris, J M, Hartman, C A, Henders, A K, Heath, A C, Hickie, I B, Hickman, M, Hopfer, C J, Hottenga, J J, Huizink, A C, Irons, D E, Kahn, R S, Korhonen, T, Kranzler, H R, Krauter, K, van Lier, P A C, Lubke, G H, Madden, P A F, Mägi, R, McGue, M K, Medland, S E, Meeus, W H J, Miller, M B, Montgomery, G W, Nivard, M G, Nolte, I M, Oldehinkel, A J, Pausova, Z, Qaiser, B, Quaye, L, Ramos-Quiroga, J A, Richarte, V, Rose, R J, Shin, J, Stallings, M C, Stiby, A I, Wall, T L, Wright, M J, Koot, H M, Paus, T, Hewitt, J K, Ribasés, M, Kaprio, J, Boks, M P, Snieder, H, Spector, T, Munafò, M R, Metspalu, A, Gelernter, J, Boomsma, D I, Iacono, W G, Martin, N G, Gillespie, N A, Derks, E M, Vink, J M
Publicado no Transl Psychiatry (2016)

International Cannabis Consortium

Por Stringer, Sven, Minică, Camelia C., Verweij, Karin J.H., Mbarek, Hamdi, Bernard, Manon, Derringer, Jaime, van Eijk, Kristel R., Isen, Joshua D., Loukola, Anu, Maciejewski, Dominique F., Mihailov, Evelin, van der Most, Peter J., Sánchez-Mora, Cristina, Roos, Leonie, Sherva, Richard, Walters, Raymond, Ware, Jennifer J., Abdellaoui, Abdel, Bigdeli, Timothy B., Branje, Susan J.T., Brown, Sandra A., Bruinenberg, Marcel, Casas, Miguel, Esko, Tõnu, Garcia-Martinez, Iris, Gordon, Scott D., Harris, Juliette M., Hartman, Catharina A., Henders, Anjali K., Heath, Andrew C., Hickie, Ian B., Hickman, Matthew, Hopfer, Christian J., Hottenga, Jouke Jan, Huizink, Anja C., Irons, Daniel E., Kahn, René S., Korhonen, Tellervo, Kranzler, Henry R., Krauter, Ken, van Lier, Pol A.C., Lubke, Gitta H., Madden, Pamela A.F., Mägi, Reedik, McGue, Matt K., Medland, Sarah E., Meeus, Wim H.J., Miller, Michael B., Montgomery, Grant W., Nivard, Michel G., Nolte, Ilja M., Oldehinkel, Albertine J., Pausova, Zdenka, Qaiser, Beenish, Quaye, Lydia, Ramos-Quiroga, Josep A., Richarte, Vanesa, Rose, Richard J., Shin, Jean, Stallings, Michael C., Stiby, Alex I., Wall, Tamara L., Wright, Margaret J., Koot, Hans M., Paus, Tomas, Hewitt, John K., Ribasés, Marta, Kaprio, Jaakko, Boks, Marco P., Snieder, Harold, Spector, Tim, Munafò, Marcus R., Metspalu, Andres, Gelernter, Joel, Boomsma, Dorret I., Iacono, William G., Martin, Nicholas G., Gillespie, Nathan A., Derks, Eske M., Vink, Jacqueline M.
Publicado no Drug Alcohol Depend (2017)

Genetic effects influencing risk for major depressive disorder in China and Europe

Por Bigdeli, T B, Ripke, S, Peterson, R E, Trzaskowski, M, Bacanu, S-A, Abdellaoui, A, Andlauer, T F M, Beekman, A T F, Berger, K, Blackwood, D H R, Boomsma, D I, Breen, G, Buttenschøn, H N, Byrne, E M, Cichon, S, Clarke, T-K, Couvy-Duchesne, B, Craddock, N, de Geus, E J C, Degenhardt, F, Dunn, E C, Edwards, A C, Fanous, A H, Forstner, A J, Frank, J, Gill, M, Gordon, S D, Grabe, H J, Hamilton, S P, Hardiman, O, Hayward, C, Heath, A C, Henders, A K, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Hottenga, J-J, Ising, M, Jansen, R, Kloiber, S, Knowles, J A, Lang, M, Li, Q S, Lucae, S, MacIntyre, D J, Madden, P A F, Martin, N G, McGrath, P J, McGuffin, P, McIntosh, A M, Medland, S E, Mehta, D, Middeldorp, C M, Milaneschi, Y, Montgomery, G W, Mors, O, Müller-Myhsok, B, Nauck, M, Nyholt, D R, Nöthen, M M, Owen, M J, Penninx, B W J H, Pergadia, M L, Perlis, R H, Peyrot, W J, Porteous, D J, Potash, J B, Rice, J P, Rietschel, M, Riley, B P, Rivera, M, Schoevers, R, Schulze, T G, Shi, J, Shyn, S I, Smit, J H, Smoller, J W, Streit, F, Strohmaier, J, Teumer, A, Treutlein, J, Van der Auwera, S, van Grootheest, G, van Hemert, A M, Völzke, H, Webb, B T, Weissman, M M, Wellmann, J, Willemsen, G, Witt, S H, Levinson, D F, Lewis, C M, Wray, N R, Flint, J, Sullivan, P F, Kendler, K S
Publicado no Transl Psychiatry (2017)

Genome-wide association study identifies novel locus for neuroticism and shows polygenic association with Major Depressive Disorder

Por de Moor, Marleen H.M., van den Berg, Stéphanie M., Verweij, Karin J.H., Krueger, Robert F., Luciano, Michelle, Vasquez, Alejandro Arias, Matteson, Lindsay K., Derringer, Jaime, Esko, Tõnu, Amin, Najaf, Gordon, Scott D., Hansell, Narelle K., Hart, Amy B., Seppälä, Ilkka, Huffman, Jennifer E., Konte, Bettina, Lahti, Jari, Lee, Minyoung, Miller, Mike, Nutile, Teresa, Tanaka, Toshiko, Teumer, Alexander, Viktorin, Alexander, Wedenoja, Juho, Abecasis, Goncalo R., Adkins, Daniel E., Agrawal, Arpana, Allik, Jüri, Appel, Katja, Bigdeli, Timothy B., Busonero, Fabio, Campbell, Harry, Costa, Paul T., Smith, George Davey, Davies, Gail, de Wit, Harriet, Ding, Jun, Engelhardt, Barbara E., Eriksson, Johan G., Fedko, Iryna O., Ferrucci, Luigi, Franke, Barbara, Giegling, Ina, Grucza, Richard, Hartmann, Annette M., Heath, Andrew C., Heinonen, Kati, Henders, Anjali K., Homuth, Georg, Hottenga, Jouke-Jan, Janzing, Joost, Jokela, Markus, Karlsson, Robert, Kemp, John P., Kirkpatrick, Matthew G., Latvala, Antti, Lehtimäki, Terho, Liewald, David C., Madden, Pamela A.F., Magri, Chiara, Magnusson, Patrik K.E., Marten, Jonathan, Maschio, Andrea, Medland, Sarah E., Mihailov, Evelin, Milaneschi, Yuri, Montgomery, Grant W., Nauck, Matthias, Ouwens, Klaasjan G., Palotie, Aarno, Pettersson, Erik, Polasek, Ozren, Qian, Yong, Pulkki-Råback, Laura, Raitakari, Olli T., Realo, Anu, Rose, Richard J., Ruggiero, Daniela, Schmidt, Carsten O., Slutske, Wendy S., Sorice, Rossella, Starr, John M., Pourcain, Beate St, Sutin, Angelina R., Timpson, Nicholas J., Trochet, Holly, Vermeulen, Sita, Vuoksimaa, Eero, Widen, Elisabeth, Wouda, Jasper, Wright, Margaret J., Zgaga, Lina, Scotland, Generation, Porteous, David, Minelli, Alessandra, Palmer, Abraham A., Rujescu, Dan, Ciullo, Marina, Hayward, Caroline, Rudan, Igor, Metspalu, Andres, Kaprio, Jaakko, Deary, Ian J., Räikkönen, Katri, Wilson, James F., Keltikangas-Järvinen, Liisa, Bierut, Laura J., Hettema, John M., Grabe, Hans J., van Duijn, Cornelia M., Evans, David M., Schlessinger, David, Pedersen, Nancy L., Terracciano, Antonio, McGue, Matt, Penninx, Brenda W.J.H., Martin, Nicholas G., Boomsma, Dorret I.
Publicado no JAMA Psychiatry (2015)