Small‐Molecule and Peptide Inhibitors of the Pro‐Survival Protein Mcl‐1

por Beekman, Andrew M., Howell, Lesley A.
Publicado en ChemMedChem (2015)

Identification of Small‐Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia‐1 (Mcl‐1)

por Beekman, Andrew M., O'Connell, Maria A., Howell, Lesley A.
Publicado en ChemMedChem (2015)

Peptide‐Directed Binding for the Discovery of Modulators of α‐Helix‐Mediated Protein–Protein Interactions: Proof‐of‐Concept Studies with the Apoptosis Regulator Mcl‐1...

por Beekman, Andrew Michael, O'Connell, Maria Anne, Howell, Lesley Ann
Publicado en Angew Chem Int Ed Engl (2017)

Insights into the Structure-Activity Relationship of Glycosides as Positive Allosteric Modulators Acting on P2X7 Receptors

por Piyasirananda, Waraporn, Beekman, Andrew, Ganesan, A., Bidula, Stefan, Stokes, Leanne
Publicado en Mol Pharmacol (2021)

A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase

por Beekman, Andrew Michael, Cominetti, Marco M. D., Cartwright, Oliver Charles, Boger, Dale L., Searcey, Mark
Publicado en Medchemcomm (2019)

Identification of selective protein–protein interaction inhibitors using efficient in silico peptide-directed ligand design

por Beekman, Andrew M., Cominetti, Marco M. D., Walpole, Samuel J., Prabhu, Saurabh, O'Connell, Maria A., Angulo, Jesus, Searcey, Mark
Publicado en Chem Sci (2019)

Peptide directed phthalocyanine–gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers

por Goddard, Zoë Rachael, Beekman, Andrew Michael, Cominetti, Marco M. D., O'Connell, Maria A., Chambrier, Isabelle, Cook, Michael J., Marín, María J., Russell, David A., Searcey, Mark
Publicado en RSC Med Chem (2020)