Pharmacological validation of a novel nonhuman primate measure of thermal responsivity with utility for predicting analgesic effects

by Vardigan, Joshua D, Houghton, Andrea K, Lange, Henry S, Adarayan, Emily D, Pall, Parul S, Ballard, Jeanine E, Henze, Darrell A, Uslaner, Jason M
Published in J Pain Res (2018)

Application of Pharmacokinetic-Pharmacodynamic Modeling to Inform Translation of In Vitro NaV1.7 Inhibition to In Vivo Pharmacological Response in Non-human Primate

by Ballard, Jeanine E., Pall, Parul, Vardigan, Joshua, Zhao, Fuqiang, Holahan, Marie A., Kraus, Richard, Li, Yuxing, Henze, Darrell, Houghton, Andrea, Burgey, Christopher S., Gibson, Christopher
Published in Pharm Res (2020)

Antagonism of T-type calcium channels inhibits high-fat diet–induced weight gain in mice

by Uebele, Victor N., Gotter, Anthony L., Nuss, Cindy E., Kraus, Richard L., Doran, Scott M., Garson, Susan L., Reiss, Duane R., Li, Yuxing, Barrow, James C., Reger, Thomas S., Yang, Zhi-Qiang, Ballard, Jeanine E., Tang, Cuyue, Metzger, Joseph M., Wang, Sheng-Ping, Koblan, Kenneth S., Renger, John J.
Published 2009

Discovery of Arylsulfonamide Na(v)1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile

by Roecker, Anthony J., Layton, Mark E., Pero, Joseph E., Kelly, Michael J., Greshock, Thomas J., Kraus, Richard L., Li, Yuxing, Klein, Rebecca, Clements, Michelle, Daley, Christopher, Jovanovska, Aneta, Ballard, Jeanine E., Wang, Deping, Zhao, Fuqiang, Brunskill, Andrew P. J., Peng, Xuanjia, Wang, Xiu, Sun, Haiyan, Houghton, Andrea K., Burgey, Christopher S.
Published in ACS Med Chem Lett (2021)

Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors

by Bungard, Christopher J., Williams, Peter D., Schulz, Jurgen, Wiscount, Catherine M., Holloway, M. Katharine, Loughran, H. Marie, Manikowski, Jesse J., Su, Hua-Poo, Bennett, David J., Chang, Lehua, Chu, Xin-Jie, Crespo, Alejandro, Dwyer, Michael P., Keertikar, Kartik, Morriello, Gregori J., Stamford, Andrew W., Waddell, Sherman T., Zhong, Bin, Hu, Bin, Ji, Tao, Diamond, Tracy L., Bahnck-Teets, Carolyn, Carroll, Steven S., Fay, John F., Min, Xu, Morris, William, Ballard, Jeanine E., Miller, Michael D., McCauley, John A.
Published in ACS Med Chem Lett (2017)

Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group

by Bungard, Christopher J., Williams, Peter D., Ballard, Jeanine E., Bennett, David J., Beaulieu, Christian, Bahnck-Teets, Carolyn, Carroll, Steve S., Chang, Ronald K., Dubost, David C., Fay, John F., Diamond, Tracy L., Greshock, Thomas J., Hao, Li, Holloway, M. Katharine, Felock, Peter J., Gesell, Jennifer J., Su, Hua-Poo, Manikowski, Jesse J., McKay, Daniel J., Miller, Mike, Min, Xu, Molinaro, Carmela, Moradei, Oscar M., Nantermet, Philippe G., Nadeau, Christian, Sanchez, Rosa I., Satyanarayana, Tummanapalli, Shipe, William D., Singh, Sanjay K., Truong, Vouy Linh, Vijayasaradhi, Sivalenka, Wiscount, Catherine M., Vacca, Joseph P., Crane, Sheldon N., McCauley, John A.
Published in ACS Med Chem Lett (2016)