The critical role of heme oxygenase in neutrophil migration impairment in polymicrobial sepsis

Por Freitas, Andressa, Alves-Filho, Jose Carlos, Suavinha, Marina Moreira, Spiller, Fernando, Dal-Secco, Daniela, Cunha, Fernando Queiroz
Publicado em 2007

TLR2 signaling downregulates chemokine receptor CXCR2 and impairs neutrophil migration in severe polymicrobial sepsis

Por Alves-Filho, Jose Carlos, Freitas, Andressa, Spiller, Fernando, Souto, Fabricio, Paula-Neto, Heitor, Silva, Joao Santana, Cunha, Fernando Queiroz
Publicado em 2007

Reduction of gap junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to sepsis

Por Celes, Mara Rubia Nunes, Torrez-Dueñas, Diego, Alves-Filho, Jose Carlos, Duarte, Djane Braz, Cunha, Fernando Queiroz, Rossi, Marcos Antonio
Publicado em 2007

Purinergic Cooperation Between P2Y(2) and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

Por Thorstenberg, Maria Luiza, Rangel Ferreira, Marcos Vinícius, Amorim, Natália, Canetti, Claudio, Morrone, Fernanda B., Alves Filho, José Carlos, Coutinho-Silva, Robson
Publicado no Front Immunol (2018)

CCR4 Controls the Suppressive Effects of Regulatory T Cells on Early and Late Events during Severe Sepsis

Por Molinaro, Raphael, Pecli, Cyntia, Guilherme, Rafael F., Alves-Filho, José Carlos, Cunha, Fernando Q., Canetti, Claudio, Kunkel, Steven L., Bozza, Marcelo T., Benjamim, Claudia F.
Publicado no PLoS One (2015)

IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system

Por Franca, Rafael F. O., Costa, Renata S., Silva, Jaqueline R., Peres, Raphael S., Mendonça, Leila R., Colón, David F., Alves-Filho, José Carlos, Cunha, Fernando Q.
Publicado no J Neuroinflammation (2016)

TGFβ1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of T(H)17 cells by an AHR-independent mechanism

Por de Lima, Kalil Alves, Donate, Paula Barbim, Talbot, Jhimmy, Davoli-Ferreira, Marcela, Peres, Raphael Sanches, Cunha, Thiago Mattar, Alves-Filho, José Carlos, Cunha, Fernando Queiroz
Publicado no Cell Death Dis (2018)

PPAR-γ/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis

Por Ferreira, Ana Elisa, Sisti, Flavia, Sônego, Fabiane, Wang, Suojang, Filgueiras, Luciano, Brandt, Stephanie, Serezani, Ana Paula Moreira, Du, Hong, Cunha, Fernando Q., Alves-Filho, Jose Carlos, Serezani, Carlos Henrique
Publicado em 2014

SOCS1 is a negative regulator of metabolic reprogramming during sepsis

Por Piñeros Alvarez, Annie Rocio, Glosson-Byers, Nicole, Brandt, Stephanie, Wang, Soujuan, Wong, Hector, Sturgeon, Sarah, McCarthy, Brian Paul, Territo, Paul R., Alves-Filho, Jose Carlos, Serezani, C. Henrique
Publicado no JCI Insight (2017)

Peroxynitrite mediates neutrophil migration failure in severe polymicrobial sepsis

Por Dal-Secco, Daniela, Torres-Dueñas, Diego, Freitas, Andressa, Celes, Mara Rubia Nunes, Alves-Filho, José Carlos, Spiller, Fernando, Dalto, Vitor Faeda, Rossi, Marcos Antonio, Ferreira, Sérgio Henrique, Cunha, Fernando Queiroz
Publicado em 2007

Blockage of Eosinopoiesis by IL-17A Is Prevented by Cytokine and Lipid Mediators of Allergic Inflammation

Por Xavier-Elsas, Pedro, de Luca, Bianca, Queto, Túlio, Vieira, Bruno Marques, Masid-de-Brito, Daniela, Dahab, Elizabeth Chen, Alves Filho, José Carlos, Cunha, Fernando Q., Gaspar-Elsas, Maria Ignez C.
Publicado no Mediators Inflamm (2015)

Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis

Por Kanashiro, Alexandre, Sônego, Fabiane, Ferreira, Raphael G., Castanheira, Fernanda V.S., Leite, Caio A., Borges, Vanessa F., Nascimento, Daniele C., Cólon, David F., Alves-Filho, José Carlos, Ulloa, Luis, Cunha, Fernando Q.
Publicado no Pharmacol Res (2016)

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

Por Lima, Cristiano Xavier, Souza, Danielle Gloria, Amaral, Flavio Almeida, Fagundes, Caio Tavares, Rodrigues, Irla Paula Stopa, Alves-Filho, Jose Carlos, Kosco-Vilbois, Marie, Ferlin, Walter, Shang, Limin, Elson, Greg, Teixeira, Mauro Martins
Publicado no PLoS One (2015)

Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious

Por Sônego, Fabiane, Castanheira, Fernanda Vargas e Silva, Ferreira, Raphael Gomes, Kanashiro, Alexandre, Leite, Caio Abner Vitorino Gonçalves, Nascimento, Daniele Carvalho, Colón, David Fernando, Borges, Vanessa de Fátima, Alves-Filho, José Carlos, Cunha, Fernando Queiróz
Publicado no Front Immunol (2016)

Interleukin-10 rs2227307 and CXCR2 rs1126579 polymorphisms modulate the predisposition to septic shock

Por Cardoso, Cristina Padre, de Oliveira, Argenil José de Assis, Botoni, Fernando Antônio, Rezende, Isabela Cristina Porto, Alves-Filho, Jose Carlos, Cunha, Fernando de Queiroz, Estanislau, Juliana de Assis Silva Gomes, Magno, Luiz Alexandre Viana, Rios-Santos, Fabricio
Publicado no Mem Inst Oswaldo Cruz (2015)

Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis

Por Czaikoski, Paula Giselle, Mota, José Maurício Segundo Correia, Nascimento, Daniele Carvalho, Sônego, Fabiane, Castanheira, Fernanda Vargas e Silva, Melo, Paulo Henrique, Scortegagna, Gabriela Trentin, Silva, Rangel Leal, Barroso-Sousa, Romualdo, Souto, Fabrício Oliveira, Pazin-Filho, Antonio, Figueiredo, Florencio, Alves-Filho, José Carlos, Cunha, Fernando Queiróz
Publicado no PLoS One (2016)

Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

Por Trevelin, Silvia Cellone, dos Santos, Célio Xavier, Ferreira, Raphael Gomes, de Sá Lima, Larissa, Silva, Rangel Leal, Scavone, Cristoforo, Curi, Rui, Alves-Filho, José Carlos, Cunha, Thiago Mattar, Roxo-Júnior, Pérsio, Cervi, Maria-Célia, Laurindo, Francisco Rafael Martins, Hothersall, John Stephen, Cobb, Andrew M., Zhang, Min, Ivetic, Aleksandar, Shah, Ajay M., Lopes, Lucia Rossetti, Cunha, Fernando Queiroz
Publicado no Sci Rep (2016)

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

Por Campa, Carlo C., Silva, Rangel L., Margaria, Jean P., Pirali, Tracey, Mattos, Matheus S., Kraemer, Lucas R., Reis, Diego C., Grosa, Giorgio, Copperi, Francesca, Dalmarco, Eduardo M., Lima-Júnior, Roberto C. P., Aprile, Silvio, Sala, Valentina, Dal Bello, Federica, Prado, Douglas Silva, Alves-Filho, Jose Carlos, Medana, Claudio, Cassali, Geovanni D., Tron, Gian Cesare, Teixeira, Mauro M., Ciraolo, Elisa, Russo, Remo C., Hirsch, Emilio
Publicado no Nat Commun (2018)

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

Por Peres, Raphael Sanches, Liew, Foo Y., Talbot, Jhimmy, Carregaro, Vanessa, Oliveira, Rene D., Almeida, Sergio L., França, Rafael F. O., Donate, Paula B., Pinto, Larissa G., Ferreira, Flavia I. S., Costa, Diego L., Demarque, Daniel P., Gouvea, Dayana Rubio, Lopes, Norberto P., Queiroz, Regina Helena C., Silva, Joao Santana, Figueiredo, Florencio, Alves-Filho, Jose Carlos, Cunha, Thiago M., Ferreira, Sérgio H., Louzada-Junior, Paulo, Cunha, Fernando Q.
Publicado no Proc Natl Acad Sci U S A (2015)