Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

INTRODUCTION: Toll-like receptors (TLRs) play an important role in the recognition of microbial products and in host defense against infection. However, the massive release of inflammatory mediators into the bloodstream following TLR activation following sepsis is thought to contribute to disease pa...

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Vydáno v:PLoS One
Hlavní autoři: Lima, Cristiano Xavier, Souza, Danielle Gloria, Amaral, Flavio Almeida, Fagundes, Caio Tavares, Rodrigues, Irla Paula Stopa, Alves-Filho, Jose Carlos, Kosco-Vilbois, Marie, Ferlin, Walter, Shang, Limin, Elson, Greg, Teixeira, Mauro Martins
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492955/
https://ncbi.nlm.nih.gov/pubmed/26147469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132336
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