Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

INTRODUCTION: Toll-like receptors (TLRs) play an important role in the recognition of microbial products and in host defense against infection. However, the massive release of inflammatory mediators into the bloodstream following TLR activation following sepsis is thought to contribute to disease pa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Lima, Cristiano Xavier, Souza, Danielle Gloria, Amaral, Flavio Almeida, Fagundes, Caio Tavares, Rodrigues, Irla Paula Stopa, Alves-Filho, Jose Carlos, Kosco-Vilbois, Marie, Ferlin, Walter, Shang, Limin, Elson, Greg, Teixeira, Mauro Martins
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492955/
https://ncbi.nlm.nih.gov/pubmed/26147469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132336
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