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Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis

We determined the roles of TLR3 and TLR9 in adverse events of polymicrobial sepsis, with a focus on development of septic cardiomyopathy, progression of which we have recently shown to be complement- and histones-dependent. So Wt, TLR3-knocked out (K.O.), and TLR9-K.O. mice were subjected to polymic...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Fattahi, Fatemeh, Russell, Mark W., Malan, Elizabeth A., Parlett, Michella, Abe, Elizabeth, Zetoune, Firas S., Ward, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186377/
https://ncbi.nlm.nih.gov/pubmed/30364002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4302726
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