Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis

We determined the roles of TLR3 and TLR9 in adverse events of polymicrobial sepsis, with a focus on development of septic cardiomyopathy, progression of which we have recently shown to be complement- and histones-dependent. So Wt, TLR3-knocked out (K.O.), and TLR9-K.O. mice were subjected to polymic...

Full description

Saved in:
Bibliographic Details
Published in:Biomed Res Int
Main Authors: Fattahi, Fatemeh, Russell, Mark W., Malan, Elizabeth A., Parlett, Michella, Abe, Elizabeth, Zetoune, Firas S., Ward, Peter A.
Format: Artigo
Language:Inglês
Published: Hindawi 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186377/
https://ncbi.nlm.nih.gov/pubmed/30364002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4302726
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items