The Intracellular Amino Terminus Plays a Dominant Role in Desensitization of ATP-gated P2X Receptor Ion Channels

Por Allsopp, Rebecca C., Evans, Richard J.
Publicado em 2011

Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels

Por Allsopp, Rebecca C., Evans, Richard J.
Publicado no J Biol Chem (2015)

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATI...

Por Allsopp, Rebecca C., Lalo, Ulyana, Evans, Richard J.
Publicado em 2010

Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120

Por Allsopp, Rebecca C., Dayl, Sudad, Schmid, Ralf, Evans, Richard J.
Publicado no Sci Rep (2017)

Cysteine Scanning Mutagenesis (Residues Glu(52)–Gly(96)) of the Human P2X1 Receptor for ATP: MAPPING AGONIST BINDING AND CHANNEL GATING

Por Allsopp, Rebecca C., El Ajouz, Sam, Schmid, Ralf, Evans, Richard J.
Publicado em 2011

P2X1 receptor mobility and trafficking; regulation by receptor insertion and activation

Por Lalo, Ulyana, Allsopp, Rebecca C, Mahaut-Smith, Martyn P, Evans, Richard J
Publicado em 2010

P2X Receptor Chimeras Highlight Roles of the Amino Terminus to Partial Agonist Efficacy, the Carboxyl Terminus to Recovery from Desensitization, and Independent Regulation of Chann...

Por Allsopp, Rebecca C., Farmer, Louise K., Fryatt, Alistair G., Evans, Richard J.
Publicado em 2013

Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis(1)

Por Roberts, Jonathan A, Valente, Marie, Allsopp, Rebecca C, Watt, David, Evans, Richard J
Publicado em 2009

Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel

Por Roberts, Jonathan A., Allsopp, Rebecca C., El Ajouz, Sam, Vial, Catherine, Schmid, Ralf, Young, Mark T., Evans, Richard J.
Publicado em 2012