Poly(ADP-Ribosyl) Glycohydrolase Prevents the Accumulation of Unusual Replication Structures during Unperturbed S Phase

Por Ray Chaudhuri, Arnab, Ahuja, Akshay Kumar, Herrador, Raquel, Lopes, Massimo
Publicado no Mol Cell Biol (2015)

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA

Por Gemble, Simon, Ahuja, Akshay, Buhagiar-Labarchède, Géraldine, Onclercq-Delic, Rosine, Dairou, Julien, Biard, Denis S. F., Lambert, Sarah, Lopes, Massimo, Amor-Guéret, Mounira
Publicado no PLoS Genet (2015)

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

Por Ahuja, Akshay K., Jodkowska, Karolina, Teloni, Federico, Bizard, Anna H., Zellweger, Ralph, Herrador, Raquel, Ortega, Sagrario, Hickson, Ian D., Altmeyer, Matthias, Mendez, Juan, Lopes, Massimo
Publicado no Nat Commun (2016)

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

Por Boege, Yannick, Malehmir, Mohsen, Healy, Marc E., Bettermann, Kira, Lorentzen, Anna, Vucur, Mihael, Ahuja, Akshay K., Böhm, Friederike, Mertens, Joachim C., Shimizu, Yutaka, Frick, Lukas, Remouchamps, Caroline, Mutreja, Karun, Kähne, Thilo, Sundaravinayagam, Devakumar, Wolf, Monika J., Rehrauer, Hubert, Koppe, Christiane, Speicher, Tobias, Padrissa-Altés, Susagna, Maire, Renaud, Schattenberg, Jörn M., Jeong, Ju-Seong, Liu, Lei, Zwirner, Stefan, Boger, Regina, Hüser, Norbert, Davis, Roger J., Müllhaupt, Beat, Moch, Holger, Schulze-Bergkamen, Henning, Clavien, Pierre-Alain, Werner, Sabine, Borsig, Lubor, Luther, Sanjiv A., Jost, Philipp J., Weinlich, Ricardo, Unger, Kristian, Behrens, Axel, Hillert, Laura, Dillon, Christopher, Di Virgilio, Michela, Wallach, David, Dejardin, Emmanuel, Zender, Lars, Naumann, Michael, Walczak, Henning, Green, Douglas R., Lopes, Massimo, Lavrik, Inna, Luedde, Tom, Heikenwalder, Mathias, Weber, Achim
Publicado no Cancer Cell (2017)