Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain

Por Hey, John A., Kocis, Petr, Hort, Jakub, Abushakra, Susan, Power, Aidan, Vyhnálek, Martin, Yu, Jeremy Y., Tolar, Martin
Publicado no CNS Drugs (2018)

Clinical Pharmacokinetics and Safety of ALZ-801, a Novel Prodrug of Tramiprosate in Development for the Treatment of Alzheimer’s Disease

Por Hey, John A., Yu, Jeremy Y., Versavel, Mark, Abushakra, Susan, Kocis, Petr, Power, Aidan, Kaplan, Paul L., Amedio, John, Tolar, Martin
Publicado no Clin Pharmacokinet (2017)

A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Oral ELND005 (scyllo-Inositol) in Young Adults with Down Syndrome without Dementia

Por Rafii, Michael S., Skotko, Brian G., McDonough, Mary Ellen, Pulsifer, Margaret, Evans, Casey, Doran, Eric, Muranevici, Gabriela, Kesslak, Patrick, Abushakra, Susan, Lott, Ira T.
Publicado no J Alzheimers Dis (2017)

The Advantages of FTD Drug Development (Part 2 of FTD: The Next Therapeutic Frontier)

Por Boxer, Adam L., Gold, Michael, Huey, Edward, Hu, William T., Rosen, Howard, Kramer, Joel, Gao, Fen-Biao, Burton, Edward A., Chow, Tiffany, Kao, Aimee, Leavitt, Blair, Lamb, Bruce, Grether, Megan, Knopman, David, Cairns, Nigel J., Mackenzie, Ian, Mitic, Laura, Roberson, Erik D., Van Kammen, Daniel, Cantillon, Marc, Zahs, Kathleen, Jackson, George, Salloway, Stephen, Morris, John, Tong, Gary, Feldman, Howard, Fillit, Howard, Dickinson, Susan, Khachaturian, Zaven, Sutherland, Margaret, Abushakra, Susan, Lewcock, Joseph, Farese, Robert, Kenet, Robert O., LaFerla, Frank, Perrin, Steve, Whitaker, Steve, Honig, Lawrence, Mesulam, Marsel, Boeve, Brad, Grossman, Murray, Miller, Bruce, Cummings, Jeffrey
Publicado em 2012