Mechanism of Inhibition for BMS-791325, a Novel Non-nucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase

Por Rigat, Karen L., Lu, Hao, Wang, Ying-Kai, Argyrou, Argyrides, Fanslau, Caroline, Beno, Brett, Wang, Yi, Marcinkeviciene, Jovita, Ding, Min, Gentles, Robert G., Gao, Min, Abell, Lynn M., Roberts, Susan B.
Publicado no J Biol Chem (2014)

Potent Triazolopyridine Myeloperoxidase Inhibitors

Por Wurtz, Nicholas R., Viet, Andrew, Shaw, Scott A., Dilger, Andrew, Valente, Meriah N., Khan, Javed A., Jusuf, Sutjano, Narayanan, Rangaraj, Fernando, Gayani, Lo, Fred, Liu, Xiaoqin, Locke, Gregory A., Kopcho, Lisa, Abell, Lynn M., Sleph, Paul, Basso, Michael, Zhao, Lei, Wexler, Ruth R., Duclos, Franck, Kick, Ellen K.
Publicado no ACS Med Chem Lett (2018)

Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase

Por Johnson, James A., Tora, George, Pi, Zulan, Phillips, Monique, Yin, Xiaohong, Yang, Richard, Zhao, Lei, Chen, Alice Y., Taylor, David S., Basso, Michael, Rose, Anne, Behnia, Kamelia, Onorato, Joelle, Chen, Xue-Qing, Abell, Lynn M., Lu, Hao, Locke, Gregory, Caporuscio, Christian, Galella, Michael, Adam, Leonard P., Gordon, David, Wexler, Ruth R., Finlay, Heather J.
Publicado no ACS Med Chem Lett (2018)

PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor

Por Hangeland, Jon J., Abell, Lynn M., Adam, Leonard P., Jiang, Ji, Friends, Todd J., Haque, Lauren E., Neels, James, Onorato, Joelle M., Chen, Alice Ye A., Taylor, David S., Yin, Xiaohong, Harrity, Thomas W., Basso, Michael D., Yang, Richard, Sleph, Paul G., Gordon, David A., Huang, Christine S., Wexler, Ruth R., Finlay, Heather J., Lawrence, R. Michael
Publicado no ACS Med Chem Lett (2018)

Triazolopyrimidines identified as reversible myeloperoxidase inhibitors

Por Duclos, Franck, Abell, Lynn M., Harden, David G., Pike, Kristen, Nowak, Kimberly, Locke, Gregory A., Duke, Gerald J., Liu, Xiaoqin, Fernando, Gayani, Shaw, Scott A., Vokits, Benjamin P., Wurtz, Nicholas R., Viet, Andrew, Valente, Meriah N., Stachura, Sylwia, Sleph, Paul, Khan, Javed A., Gao, Ji, Dongre, Ashok R., Zhao, Lei, Wexler, Ruth R., Gordon, David A., Kick, Ellen K.
Publicado no Medchemcomm (2017)