Regulation of G Protein-Coupled Receptors by Allosteric Ligands

ανά Lane, J. Robert, Abdul-Ridha, Alaa, Canals, Meritxell
Έκδοση 2013

Mechanistic Insights into Allosteric Structure-Function Relationships at the M(1) Muscarinic Acetylcholine Receptor

ανά Abdul-Ridha, Alaa, Lane, J. Robert, Mistry, Shailesh N., López, Laura, Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur, Canals, Meritxell
Τόπος έκδοσης J Biol Chem (2014)

Molecular Determinants of Allosteric Modulation at the M(1) Muscarinic Acetylcholine Receptor

ανά Abdul-Ridha, Alaa, López, Laura, Keov, Peter, Thal, David M., Mistry, Shailesh N., Sexton, Patrick M., Lane, J. Robert, Canals, Meritxell, Christopoulos, Arthur
Έκδοση 2014

Diazepam is not a direct allosteric modulator of α(1)‐adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase‐4

ανά Williams, Lisa M., He, Xiaoji, Vaid, Tasneem M., Abdul‐Ridha, Alaa, Whitehead, Alice R., Gooley, Paul R., Bathgate, Ross A.D., Williams, Spencer J., Scott, Daniel J.
Τόπος έκδοσης Pharmacol Res Perspect (2018)

Gram scale preparation of clozapine N-oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs

ανά van der Peet, Phillip L., Gunawan, Christian, Abdul-Ridha, Alaa, Ma, Sherie, Scott, Daniel J., Gundlach, Andrew L., Bathgate, Ross A.D., White, Jonathan M., Williams, Spencer J.
Τόπος έκδοσης MethodsX (2018)

Probing the correlation between ligand efficacy and conformational diversity at the α(1A)-adrenoreceptor reveals allosteric coupling of its microswitches

ανά Wu, Feng-Jie, Williams, Lisa M., Abdul-Ridha, Alaa, Gunatilaka, Avanka, Vaid, Tasneem M., Kocan, Martina, Whitehead, Alice R., Griffin, Michael D. W., Bathgate, Ross A. D., Scott, Daniel J., Gooley, Paul R.
Τόπος έκδοσης J Biol Chem (2020)