Clinical impact, diagnosis and control of Equine Herpesvirus‐1 infection in Europe

Por European Food Safety Authority (EFSA), Andrea Carvelli, Søren Saxmose Nielsen, Romain Paillot, Alessandro Broglia, Lisa Kohnle
Publicado em 2022-04-01

Safety Evaluation of Topical Application of Nano-Liposomal Form of Amphotericin B (SinaAmpholeish) on Healthy Volunteers: Phase I Clinical Trial

Por ESKANDARI, Seyed Ebrahim, FIROOZ, Alireza, NASSIRI-KASHANI, Mansour, JAAFARI, Mahmoud Reza, JAVADI, Amir, MIRAMIN MOHAMMADI, Akram, KHAMESIPOUR, Ali
Publicado no Iran J Parasitol (2019)

Phase I Clinical Trial of an Adenovirus/PSA Vaccine for Prostate Cancer: Safety and Immunologic Results

Por Lubaroff, David M., Konety, Badrinath R., Link, Brian, Gerstbrein, Jack, Madsen, Tammy, Shannon, Mary, Howard, Jeanne, Paisley, Jennifer, Boeglin, Diana, Ratliff, Timothy L., Williams, Richard D.
Publicado em 2009

Efficacy and safety of ozonated autohemotherapy in patients with hyperuricemia and gout: A phase I pilot study

Por LI, LIAN-YUN, NI, JIA-XIANG
Publicado em 2014

An Open-Label, Phase II Study of the Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (PIPF-002)

Por Gotfried, Mark H., Girod, Carlos E., Antin-Ozerkis, Danielle, Burgess, Tracy, Strombom, Indiana, Stauffer, John L., Kirchgaessler, Klaus-Uwe, Padilla, Maria L.
Publicado no Pulm Ther (2018)

Randomized phase 2 trial of NP001–a novel immune regulator: Safety and early efficacy in ALS

Por Miller, Robert G., Block, Gilbert, Katz, Jonathan S., Barohn, Richard J., Gopalakrishnan, Vidhya, Cudkowicz, Merit, Zhang, Jane R., McGrath, Michael S., Ludington, Elizabeth, Appel, Stan H., Azhir, Ari
Publicado no Neurol Neuroimmunol Neuroinflamm (2015)

A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia

Por Tao Wang, Weihong Kuang, Wei Chen, Wenwei Xu, Liming Zhang, Yingjie Li, Hailin Li, Ying Peng, Yangmei Chen, Baojun Wang, Jinsong Xiao, Honghua Li, Chuanzhu Yan, Yifeng Du, Mouni Tang, Zhiyi He, Haibo Chen, Wei Li, Hong Lin, Shugui Shi, Jianzhong Bi, Huadong Zhou, Yan Cheng, Xiaoping Gao, Yihui Guan, Qiu Huang, Kewei Chen, Xianliang Xin, Jian Ding, Meiyu Geng, Shifu Xiao
Publicado em 2020-09-01

Safety and Immunogenicity of DNA Vaccines Encoding Ebolavirus and Marburgvirus Wild-Type Glycoproteins in a Phase I Clinical Trial

Por Sarwar, Uzma N., Costner, Pamela, Enama, Mary E., Berkowitz, Nina, Hu, Zonghui, Hendel, Cynthia S., Sitar, Sandra, Plummer, Sarah, Mulangu, Sabue, Bailer, Robert T., Koup, Richard A., Mascola, John R., Nabel, Gary J., Sullivan, Nancy J., Graham, Barney S., Ledgerwood, Julie E.
Publicado no J Infect Dis (2015)

The Safety and Immunogenicity of Live Zoster Vaccination in Patients With Rheumatoid Arthritis Before Starting Tofacitinib: A Randomized Phase II Trial

Por Winthrop, Kevin L., Wouters, Ann G., Choy, Ernest H., Soma, Koshika, Hodge, Jennifer A., Nduaka, Chudy I., Biswas, Pinaki, Needle, Elie, Passador, Sherry, Mojcik, Christopher F., Rigby, William F.
Publicado no Arthritis Rheumatol (2017)

Safety and Pharmacokinetics of Intravenous Zanamivir Treatment in Hospitalized Adults With Influenza: An Open-label, Multicenter, Single-Arm, Phase II Study

Por Marty, Francisco M., Man, Choy Y., van der Horst, Charles, Francois, Bruno, Garot, Denis, Máňez, Rafael, Thamlikitkul, Visanu, Lorente, José A., Álvarez-Lerma, Francisco, Brealey, David, Zhao, Henry H., Weller, Steve, Yates, Phillip J., Peppercorn, Amanda F.
Publicado em 2014

Safety and tolerability of injectable Rilpivirine LA in HPTN 076: A phase 2 HIV pre-exposure prophylaxis study in women

Por Bekker, L.G., Li, S., Pathak, S., Tolley, E.E., Marzinke, M.A., Justman, J.E., Mgodi, N.M., Chirenje, M., Swaminathan, S., Adeyeye, A., Farrior, J., Hendrix, C.W., Piwowar-Manning, E., Richardson, P., Eshelman, S.H., Redinger, H., Williams, P., Sista, N.D.
Publicado no EClinicalMedicine (2020)

Safety, Tolerability, and Efficacy of Azilsartan Medoxomil With or Without Chlorthalidone During and After 8 Months of Treatment for Hypertension

Por Kipnes, Mark S., Handley, Alison, Lloyd, Eric, Barger, Bruce, Roberts, Andrew
Publicado no J Clin Hypertens (Greenwich) (2015)

Efficacy and Safety of Umbilical Cord Mesenchymal Stem Cell Therapy for Rheumatoid Arthritis Patients: A Prospective Phase I/II Study

Por Wang L, Huang S, Li S, Li M, Shi J, Bai W, Wang Q, Zheng L, Liu Y
Publicado em 2019-12-01

A phase I clinical study to evaluate safety of orally administered, genetically engineered Salmonella enterica serovar Typhimurium for canine osteosarcoma

Por Fritz, Sara E., Henson, Michael S., Greengard, Emily, Winter, Amber L., Stuebner, Kathleen M., Yoon, Una, Wilk, Vicki L., Borgatti, Antonella, Augustin, Lance B., Modiano, Jaime F., Saltzman, Daniel A.
Publicado no Vet Med Sci (2016)

Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine.

Por Sandhya Vasan, Sarah J Schlesinger, Zhiwei Chen, Arlene Hurley, Angela Lombardo, Soe Than, Phumla Adesanya, Catherine Bunce, Mark Boaz, Rosanne Boyle, Eddy Sayeed, Lorna Clark, Daniel Dugin, Mar Boente-Carrera, Claudia Schmidt, Qing Fang, LeiBa, Yaoxing Huang, Gerasimos J Zaharatos, David F Gardiner, Marina Caskey, Laura Seamons, Martin Ho, Len Dally, Carol Smith, Josephine Cox, Dilbinder Gill, Jill Gilmour, Michael C Keefer, Patricia Fast, David D Ho
Publicado em 2010-01-01

Phase 1 Safety and Immunogenicity Evaluation of ADMVA, a Multigenic, Modified Vaccinia Ankara-HIV-1 B'/C Candidate Vaccine

Por Vasan, Sandhya, Schlesinger, Sarah J., Chen, Zhiwei, Hurley, Arlene, Lombardo, Angela, Than, Soe, Adesanya, Phumla, Bunce, Catherine, Boaz, Mark, Boyle, Rosanne, Sayeed, Eddy, Clark, Lorna, Dugin, Daniel, Boente-Carrera, Mar, Schmidt, Claudia, Fang, Qing, Lei, Huang, Yaoxing, Zaharatos, Gerasimos J., Gardiner, David F., Caskey, Marina, Seamons, Laura, Ho, Martin, Dally, Len, Smith, Carol, Cox, Josephine, Gill, Dilbinder, Gilmour, Jill, Keefer, Michael C., Fast, Patricia, Ho, David D.
Publicado em 2010

Efficacy, safety, and tolerability of once‐daily abediterol in patients with stable, persistent asthma: a Phase II, randomized, 7‐day, crossover study

Por Beier, Jutta, Fuhr, Rainard, Seoane, Beatriz, Massana, Eric, de Miquel, Gonzalo, Pujol, Helena, Ruiz, Sandrine
Publicado no Pharmacol Res Perspect (2017)

Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials

Por Gaudinski, Martin R, Houser, Katherine V, Morabito, Kaitlyn M, Hu, Zonghui, Yamshchikov, Galina, Rothwell, Ro Shauna, Berkowitz, Nina, Mendoza, Floreliz, Saunders, Jamie G, Novik, Laura, Hendel, Cynthia S, Holman, LaSonji A, Gordon, Ingelise J, Cox, Josephine H, Edupuganti, Srilatha, McArthur, Monica A, Rouphael, Nadine G, Lyke, Kirsten E, Cummings, Ginny E, Sitar, Sandra, Bailer, Robert T, Foreman, Bryant M, Burgomaster, Katherine, Pelc, Rebecca S, Gordon, David N, DeMaso, Christina R, Dowd, Kimberly A, Laurencot, Carolyn, Schwartz, Richard M, Mascola, John R, Graham, Barney S, Pierson, Theodore C, Ledgerwood, Julie E, Chen, Grace L
Publicado no Lancet (2018)

Study protocol of the SACURA trial: a randomized phase III trial of efficacy and safety of UFT as adjuvant chemotherapy for stage II colon cancer

Por Ishiguro, Megumi, Mochizuki, Hidetaka, Tomita, Naohiro, Shimada, Yasuhiro, Takahashi, Keiichi, Kotake, Kenjiro, Watanabe, Masahiko, Kanemitsu, Yukihide, Ueno, Hideki, Ishikawa, Toshiaki, Uetake, Hiroyuki, Matsui, Shigeyuki, Teramukai, Satoshi, Sugihara, Kenichi
Publicado em 2012

Nusinersen initiated in infants during the presymptomatic stage of spinal muscular atrophy: Interim efficacy and safety results from the Phase 2 NURTURE study

Por De Vivo, Darryl C., Bertini, Enrico, Swoboda, Kathryn J., Hwu, Wuh-Liang, Crawford, Thomas O., Finkel, Richard S., Kirschner, Janbernd, Kuntz, Nancy L., Parsons, Julie A., Ryan, Monique M., Butterfield, Russell J., Topaloglu, Haluk, Ben-Omran, Tawfeg, Sansone, Valeria A., Jong, Yuh-Jyh, Shu, Francy, Staropoli, John F., Kerr, Douglas, Sandrock, Alfred W., Stebbins, Christopher, Petrillo, Marco, Braley, Gabriel, Johnson, Kristina, Foster, Richard, Gheuens, Sarah, Bhan, Ishir, Reyna, Sandra P., Fradette, Stephanie, Farwell, Wildon
Publicado no Neuromuscul Disord (2019)