Resultados da pesquisa - ((drug doses) or (drug dose)) devel them*

1

Low-dose modified-release prednisone in axial spondyloarthritis: 3-month efficacy and tolerability

Por Bandinelli, Francesca, Scazzariello, Francesco, Pimenta da Fonseca, Emanuela, Barreto Santiago, Mittermayer, Marcassa, Claudio, Nacci, Francesca, Matucci Cerinic, Marco
Publicado no Drug Des Devel Ther (2016)

“...-release prednisone taken in the morning. The efficacy of low-dose MR prednisolone in patients with SpA...”
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Identification of PPARγ ligands with One-dimensional Drug Profile Matching

Por Kovács, Diána, Simon, Zoltán, Hári, Péter, Málnási-Csizmadia, András, Hegedűs, Csaba, Drimba, László, Németh, József, Sári, Réka, Szilvássy, Zoltán, Peitl, Barna
Publicado em 2013

“... needed for drug development. Reintroduction of generic drugs by second medical use patents also...”
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3

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Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf(®) within a pressurized metered dose inhaler: a Calu-3 model

Por van Rensburg, Lyné, van Zyl, Johann M, Smith, Johan
Publicado no Drug Des Devel Ther (2018)

“... Generation Impactor™. RESULTS: The delivered particles and drug dose showed a high dependency from...”
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4

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New developments in the management of partial-onset epilepsy: role of brivaracetam

Por Coppola, Giangennaro, Iapadre, Giulia, Operto, Francesca Felicia, Verrotti, Alberto
Publicado no Drug Des Devel Ther (2017)

“... metabolism and drug interactions. Many of them still need to be further evaluated mainly in real-world...”
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Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

Por Jang, Kyungho, Yoon, Seonghae, Kim, Sung-Eun, Cho, Joo-Youn, Yoon, Seo Hyun, Lim, Kyoung Soo, Yu, Kyung-Sang, Jang, In-Jin, Lee, Howard
Publicado em 2014

“... and tolerability of the nanocrystal formulation and to compare them with those of Megace(®) OS in the fed...”
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6

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BCc1, the novel antineoplastic nanocomplex, showed potent anticancer effects in vitro and in vivo

Por Kalanaky, Somayeh, Hafizi, Maryam, Fakharzadeh, Saideh, Vasei, Mohammad, Langroudi, Ladan, Janzamin, Ehsan, Hashemi, Seyed Mahmoud, Khayamzadeh, Maryam, Soleimani, Masoud, Akbari, Mohammad Esmaeil, Nazaran, Mohammad Hassan
Publicado no Drug Des Devel Ther (2015)

“... nanocomplex. For the in vivo study, mammary tumor-bearing female Balb/c mice were treated with different doses...”
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Evaluation of the antitumor activity of NOV202, a novel microtubule targeting and vascular disrupting agent

Por Rickardson, Linda, Kutvonen, Emma, Orasniemi, Satu, Högberg, Marita, Kallio, Marko J, Rehnmark, Stefan
Publicado no Drug Des Devel Ther (2017)

“... and antiangiogenic properties that make them effective on refractory tumors. METHODS: Permeability of NOV202...”
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8

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Diverse pathomechanisms leading to the breakdown of cellular estrogen surveillance and breast cancer development: new therapeutic strategies

Por Suba, Zsuzsanna
Publicado em 2014

“... of pathologic processes and both of them may lead to breast cancer development. Primary insulin resistance...”
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9

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Differential benefit risk assessment of DOACs in the treatment of venous thromboembolism: focus on dabigatran

Por Leung, Timothy S, Law, Ernest H
Publicado no Drug Des Devel Ther (2015)

“... thromboembolism. Clinical trials comparing DOACs with standard therapy have shown them to be non-inferior...”
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Effect of N-methyl deuteration on metabolism and pharmacokinetics of enzalutamide

Por Jiang, Jinfang, Pang, Xuehai, Li, Liang, Dai, Xiaojian, Diao, Xingxing, Chen, Xiaoyan, Zhong, Dafang, Wang, Yingwei, Chen, Yuanwei
Publicado no Drug Des Devel Ther (2016)

“... for the treatment of metastatic castration-resistant prostate cancer by the US Food and Drug Administration in 2012...”
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Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) as second-line chemotherapy in HER2-negative, taxane-pretreated metastatic breast cancer patients: prospective evaluation of...

Por Palumbo, Raffaella, Sottotetti, Federico, Trifirò, Giuseppe, Piazza, Elena, Ferzi, Antonella, Gambaro, Anna, Spinapolice, Elena Giulia, Pozzi, Emma, Tagliaferri, Barbara, Teragni, Cristina, Bernardo, Antonio
Publicado no Drug Des Devel Ther (2015)

“... at the dose of 260 mg/m(2) as a 30-minute intravenous infusion on day 1 each treatment cycle, which lasted 3...”
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New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant pat...

Por Kim, Yu Kyong, Kim, Anhye, Park, Shin Jung, Lee, Howard
Publicado no Drug Des Devel Ther (2017)

“... of tacrolimus and its interindividual variability (IIV) in the systemic exposure, and to compare them with those...”
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D-cycloserine augmentation in behavioral therapy for obsessive-compulsive disorder: a meta-analysis

Por Xia, Jing, Du, Yanqiu, Han, Jiyang, Liu, Guo, Wang, Xumei
Publicado no Drug Des Devel Ther (2015)

“.... Among them, four were for analyses of DCS and Y-BOCS at midtreatment, six for analysis at posttreatment...”
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