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Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf(®) within a pressurized metered dose inhaler: a Calu-3 model

BACKGROUND: Previous studies in our laboratory demonstrated that a synthetic peptide containing lung surfactant enhances the permeability of chemical compounds through bronchial epithelium. The purpose of this study was to test two formulations of Synsurf(®) combined with linezolid as respirable com...

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Dettagli Bibliografici
Pubblicato in:Drug Des Devel Ther
Autori principali: van Rensburg, Lyné, van Zyl, Johann M, Smith, Johan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5942168/
https://ncbi.nlm.nih.gov/pubmed/29765201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S147035
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