Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state

BACKGROUND: Megestrol acetate is an effective treatment for improving appetite and increasing body weight in patients with cancer-associated anorexia. However, Megace(®) oral suspension (OS), a micronized formulation of megestrol acetate, has low bioavailability in the fasting state. To overcome thi...

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Detalhes bibliográficos
Main Authors: Jang, Kyungho, Yoon, Seonghae, Kim, Sung-Eun, Cho, Joo-Youn, Yoon, Seo Hyun, Lim, Kyoung Soo, Yu, Kyung-Sang, Jang, In-Jin, Lee, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077389/
https://ncbi.nlm.nih.gov/pubmed/25028536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S62176
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